A0A4V1WQN2 · A0A4V1WQN2_ALTAL
- ProteinFatty acid synthase subunit alpha
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1862 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- a (3R)-hydroxyacyl-[ACP] + NADP+ = a 3-oxoacyl-[ACP] + H+ + NADPH
Pathway
Mycotoxin biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 1281 | For beta-ketoacyl synthase activity | ||||
Sequence: C | ||||||
Binding site | 1748 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 1748-1750 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: DVE | ||||||
Binding site | 1749 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 1750 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 1774 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 1784 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 1793-1809 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: EAVFKSLGVKGQGAGAP | ||||||
Binding site | 1817-1820 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: NNES | ||||||
Binding site | 1847-1849 | acetyl-CoA (UniProtKB | ChEBI) | ||||
Sequence: ISH | ||||||
Binding site | 1848 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 1849 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | fatty acid synthase complex | |
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity | |
Molecular Function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | |
Molecular Function | fatty acid synthase activity | |
Molecular Function | fatty-acyl-CoA synthase activity | |
Molecular Function | holo-[acyl-carrier-protein] synthase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | long-chain fatty acid biosynthetic process | |
Biological Process | secondary metabolite biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameFatty acid synthase subunit alpha
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Pleosporineae > Pleosporaceae > Alternaria > Alternaria sect. Alternaria > Alternaria alternata complex
Accessions
- Primary accessionA0A4V1WQN2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 179 | O-(pantetheine 4'-phosphoryl)serine | ||||
Sequence: S |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 98-140 | Disordered | ||||
Sequence: EPEAPAASSGGASSAPASAPSASAPAAVAAPPPPSAGPAAQVP | ||||||
Compositional bias | 123-137 | Pro residues | ||||
Sequence: AAVAAPPPPSAGPAA | ||||||
Domain | 144-219 | Carrier | ||||
Sequence: VTATDIVRTLVAQKLKKPLVDIPLSKAIKDLVGGKSTLQNEILGDLGKEFGSTPEKPEDTPLDELGAAMQATFNGQ | ||||||
Domain | 1098-1636 | Ketosynthase family 3 (KS3) | ||||
Sequence: MQEIQIEEDLDPFEASKETAEEFKLEHGDKVEIFAIEGSAEYTVRMKKGATLLLPKALRFDRLVAGQVPTGWDAKKYGVPDDIISQVDPVTLFVLVSTAECLLASGITDPYEFYKYVHISQVGNCVGSGIGGTTALRGMYKDRFMDKPVQKDILQESFINTMSAWVNMLLLSSTGPIKTPVGACATAVESLDIGYDTIVEGKARVCFVGGFDDFQEEGSYEFANMKATSNAEDEFAHGRTPKEMSRPATTTRNGFMESQGCGMQVIMDAKLALDMGVPIYGILGFTATATDKIGRSVPAPGKGVLTTARETPSKFPSPLLDIKYRRRQMDLRRKQIKQWQESEILYLQEEVAAMKDATGEDFDEAAYLEERASNIEMEAKRQEKDALNSLGNNFWKQDSRIAPLRGALATWGLTIDDLDVASFHGTSTMANDKNESDVINHQMRHLGRKKGNALLSIWQKHLTGHPKGAAGAWMFNGCLQVLNSGLVPGNPNADNIDKNMEQFDYIVYPSQSIQTDGVKAFSVTSFGFGQKGSQAIGIH | ||||||
Region | 1330-1351 | Disordered | ||||
Sequence: DEFAHGRTPKEMSRPATTTRNG |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,862
- Mass (Da)205,299
- Last updated2019-07-31 v1
- Checksum69AFBAA738F6F19F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 123-137 | Pro residues | ||||
Sequence: AAVAAPPPPSAGPAA |