A0A4U3LBU7 · A0A4U3LBU7_9ACTN

  • Protein
    NADH-quinone oxidoreductase subunit N
  • Gene
    nuoN
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological ProcessATP synthesis coupled electron transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit N
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit N
    • NDH-1 subunit N

Gene names

    • Name
      nuoN
    • ORF names
      FDA38_25745
      , FDA38_41310

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NEAU-THZ 27
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Kribbellaceae > Kribbella

Accessions

  • Primary accession
    A0A4U3LBU7

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-38Helical
Transmembrane45-66Helical
Transmembrane86-104Helical
Transmembrane141-157Helical
Transmembrane163-184Helical
Transmembrane196-218Helical
Transmembrane238-263Helical
Transmembrane275-296Helical
Transmembrane308-327Helical
Transmembrane334-358Helical
Transmembrane370-391Helical
Transmembrane412-432Helical
Transmembrane452-476Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain158-461NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    526
  • Mass (Da)
    54,994
  • Last updated
    2019-07-31 v1
  • Checksum
    93148FA27F48705B
MLLPLADFTAPKIEYNELAPLLVVFGAACVGVLVEAFLPRSLRHLVQLSITVVAVVVSGVLTGILMNDNKELIAAQGAISVDGPALFTWLILLALTLISVLLFAERSIDGGLSAFAGQAAAVPGSEAEREGTAARIEHTEIFPLTLFAVGGMMLFAASNDLLVLFVALEVFSLPLYLLCGLARRRRLISQEAAMKYFLLGAFSSAFLLFGIALLYGYAGTMSLGGIADALSTQTGGDTILLAGTGLVGVGLLFKVGGVPFHSWTPDVYQGAPTPVTGFMAACTKIAAFVGLMRVFYVALGGTRWDWAPMMWIVAILTMVIGSIVAITQTDVKRMLAYSSIAHAGFLLTAFVGLAQAGSGVHNGITSTQAVLFYLVSYGFPTIGAFAVVTLVRDAGGEATHLSRWAGLGKKSPLLAGIFAFFLLSFAGIPLTAGFTGKWAVFSAAWTGGAWPLVVVAVLSSLVAAFFYVRVIVLMFFSDLPADAPDVALPGWQTTSAVALGLAATVVLGLVPGPVLDLAARAGEFIR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SZPZ01000008
EMBL· GenBank· DDBJ
TKK72885.1
EMBL· GenBank· DDBJ
Genomic DNA
SZPZ01000003
EMBL· GenBank· DDBJ
TKK78641.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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