A0A4U1L2S6 · A0A4U1L2S6_9SPHN

  • Protein
    Bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada
  • Gene
    ada
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for active site, binding site.

134850100150200250300
TypeIDPosition(s)Description
Active site37Nucleophile; methyl group acceptor from methylphosphotriester
Binding site37Zn2+ (UniProtKB | ChEBI)
Binding site41Zn2+ (UniProtKB | ChEBI)
Binding site68Zn2+ (UniProtKB | ChEBI)
Binding site71Zn2+ (UniProtKB | ChEBI)
Active site316Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionmethylated-DNA-[protein]-cysteine S-methyltransferase activity
Molecular Functionsequence-specific DNA binding
Molecular Functionzinc ion binding
Biological ProcessDNA repair
Biological Processmethylation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada

Gene names

    • Name
      ada
    • ORF names
      FBR43_10680

Organism names

  • Taxonomic identifier
  • Strain
    • L-1-4w-11
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas

Accessions

  • Primary accession
    A0A4U1L2S6

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain84-182HTH araC/xylS-type

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    348
  • Mass (Da)
    36,508
  • Last updated
    2019-07-31 v1
  • Checksum
    8F48DB2B966895E2
MSSAAISDAAAWAAFERRDRAFDGRFVGAVVTTGIYCRPSCPARRPLREHMRFYPDAAAARDAGFRACMRCLPDAVARDRAAVDAALAILDSAAPDAPPSLEGLAARVGYAPHHFHRLFKRATGVTPAAYARAHRTARAAALLHEENAVSDAIYAAGYSAPSRFYAETGARLGMTPSAWKAGGRGVTIGWTIAETSLGPLLIAATERGLCRVAFGEDAAALAVRFPHAEIRPGDEALAALAARVVAEVEAPGRDRDLPLDVQGTAFQEAIWQALRAIPPGSSISYAELAARVGKPGAVRAASSACGANHVAVAIPCHRVARSDGSLGGYAYGLDIKAELRRREGVAGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SWKR01000002
EMBL· GenBank· DDBJ
TKD51169.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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