A0A4T1ZZC2 · A0A4T1ZZC2_9PSED
- Proteinlactoylglutathione lyase
- GenegloA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids130 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (R)-S-lactoylglutathione = methylglyoxal + glutathione
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
Pathway
Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 56 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
Binding site | 74 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
Active site | 122 | Proton donor/acceptor | |||
Binding site | 122 | Zn2+ (UniProtKB | ChEBI); ligand shared between dimeric partners | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | lactoylglutathione lyase activity | |
Molecular Function | metal ion binding | |
Biological Process | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namelactoylglutathione lyase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A4T1ZZC2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length130
- Mass (Da)14,538
- Last updated2019-07-31 v1
- MD5 ChecksumA3DF66D093589351CF55CA8D0C2EE1AB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
RFLV01000001 EMBL· GenBank· DDBJ | TIH09212.1 EMBL· GenBank· DDBJ | Genomic DNA |