A0A4T1ZVH2 · A0A4T1ZVH2_9PSED

  • Protein
    oxoglutarate dehydrogenase (succinyl-transferring)
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentoxoglutarate dehydrogenase complex
Molecular Functionoxoglutarate dehydrogenase (succinyl-transferring) activity
Molecular Functionthiamine pyrophosphate binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    oxoglutarate dehydrogenase (succinyl-transferring)
  • EC number

Gene names

    • ORF names
      D8779_12590

Organism names

  • Taxonomic identifier
  • Strain
    • CCM 8849
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A4T1ZVH2

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain599-792Transketolase-like pyrimidine-binding

Sequence similarities

Belongs to the alpha-ketoglutarate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    943
  • Mass (Da)
    106,299
  • Last updated
    2019-07-31 v1
  • Checksum
    EC9DF087311CAD97
MQESVMQRMWDSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFQKLPTDGSAATDVSHSTVRDHFVLLAKNQRRAQPVSAGSVSSEHEKKQVEVLRLIQAYRMRGHQAAQLDPLGLWQRPAPADLAINHYGLTDADLDTTFRTGGLFIGKEEATLREIHDALQQTYCRTIGAEFTHIVDSEQRSWFQQRLESVRGRPQISVEMQSHLLERLTAAEGLEKYLGTKYPGTKRFGLEGGESLIPLLDEVIQRSGSYGTKEIVIGMAHRGRLNVLVNTFGKNPRDLFDEFEGKKTEGLSSGDVKYHQGFSSNVMTAGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRNDAAGEKVLPVSLHGDAAFAGQGVVMETFQMSQTRGFKTGGTIHIVINNQVGFTISNPLDSRSTEYCTDVAKMIQAPILHVNGDDPEAVLFVTQLAVDYRMQYKRDVVIDLVCYRRRGHNEADEPSGTQPIMYQQITKQRTTRELYAEVLTGAARQSADEVQAKIDEYRTALDNGQHVVKSLVKEPNKELFVDWRPYLGHAWTARHDTRFELKTLQELSNKLLEIPEGFVVQRQVAKILEDRQKMGVGALPINWGYAETMAYATLLFEGHPIRMTGQDIGRGTFSHRHAVLHNQKDAGTHLPLQNLYAAQPKFDLYDSFLSEEAVLAFEYGYATTQPQSLVIWEAQFGDFANGAQVVFDQFISSGEHKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEHNMQVAVPTTPAQIYHLLRRQVIRPLRKPLVVLTPKSLLRHKLAISTLEDLAEGSFQTVIPEIDSIDPKKVDRLVLCSGKVYYDLLEKRRNEGREDIAIVRIEQLYPFPEDDLNEALAPYKNLKHIVWCQEEPMNQGAWYCSQHHMRRVATAHKKTLFLEYAGRDASAAPACGYASLHAEQQEKLLQDAFTV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RFLV01000002
EMBL· GenBank· DDBJ
TIH08345.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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