A0A4S2QT52 · A0A4S2QT52_9RICK

Function

function

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

1937100200300400500600700800900
TypeIDPosition(s)Description
Binding site29-36ATP (UniProtKB | ChEBI)
Binding site630-637ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentexcinuclease repair complex
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Molecular Functionexcinuclease ABC activity
Molecular Functionzinc ion binding
Biological Processnucleotide-excision repair
Biological ProcessSOS response

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    UvrABC system protein A
  • Short names
    UvrA protein
  • Alternative names
    • Excinuclease ABC subunit A

Gene names

    • Name
      uvrA
    • ORF names
      EJE47_05520

Organism names

Accessions

  • Primary accession
    A0A4S2QT52

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Forms a heterotetramer with UvrB during the search for lesions.

Family & Domains

Features

Showing features for domain, zinc finger.

TypeIDPosition(s)Description
Domain597-926ABC transporter
Zinc finger729-755C4-type

Sequence similarities

Belongs to the ABC transporter superfamily. UvrA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    937
  • Mass (Da)
    103,780
  • Last updated
    2019-07-31 v1
  • Checksum
    D4289BB1FDC1EF33
MIRVKGAREHNLQGIDVDIPKNKLVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLNIQDKPDVELITGLSPAISINQKSISKNPRSTVGTVTEIYDYVRLIYARVGIPYSPVTGLPITKQAVSQIVDTIIALPLETKIYILAPIVRGRKGEHFKEILEIKKQGYVRLKIDGETYNIDDLPKLDKNKKHDIFVIADRISISDDIGNRLPSSVESALRLGHGLMYAEIVNLPDNHSSEYKNGQTLTFSENFACPESGFTLEEIEPRLFSFNSPYGACSSCNGLGKKLSVDAKLIVPDETLSISEGALKPIGSIFRQVHTNYGLLKNAILSLAENCKFSLDVPWKNIDQKVKDLILFGSREIKFQGLVSILERQMDYDASLIDRYCSVTDCKECVGYRLRKEALTVKIDEKHIGEISRLSIDESLKWFGNLSDRLTEQQRQISNKILNEIIKRLTFLKNVGLNYLTLDRESSTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQCDNDRLITTLKNLRDMGNTVIVVEHDEDTIMAADYVIDIGPGAGVNGGKIVAEGTPDQVQKNSESITGQYLSGKKEISISKRRKQTTQFIKVVNACENNLKNINVEFPIGNFICVTGISGGGKSSLVIETLYKYSAHKINHSSARHGRCDKIEGLEYIDKIIEVDQSPIGRTPASNPATYVGMFTHIRNWFAGLPESKARGYNVGRFSFNTKGGRCEACKGDGHLKIEMHFLPDVYVKCEQCRGQRYNRETLEVTYKGKSISDVLGMTIDQACDFFADLPMIKEKLISLQEVGLGYITLGQSSTTLSGGEAQRIKLSKELSKRFTGKTLYILDEPTTGLHFEDVNNLLKILHRLVDLGNTVIVIEHNLHVIKTADHIIDIGPEGGVKGGKVVAVGTPEKVAQTPESVTGKYLKTYLLDQVSTIS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RWIK01000008
EMBL· GenBank· DDBJ
THA19767.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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