A0A4R8EUR4 · A0A4R8EUR4_9BACT
- ProteinMultifunctional fusion protein
- GenetpiA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids655 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 21-23 | substrate | |||
Binding site | 36 | substrate | |||
Binding site | 59-62 | substrate | |||
Binding site | 118 | substrate | |||
Binding site | 151 | substrate | |||
Binding site | 201 | ATP (UniProtKB | ChEBI) | |||
Binding site | 293 | ATP (UniProtKB | ChEBI) | |||
Binding site | 324 | ATP (UniProtKB | ChEBI) | |||
Binding site | 353-356 | ATP (UniProtKB | ChEBI) | |||
Binding site | 410-412 | substrate | |||
Active site | 496 | Electrophile | |||
Active site | 568 | Proton acceptor | |||
Binding site | 574 | substrate | |||
Binding site | 614 | substrate | |||
Binding site | 635-636 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ADP binding | |
Molecular Function | ATP binding | |
Molecular Function | phosphoglycerate kinase activity | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glycolytic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
- Recommended namePhosphoglycerate kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermotogota > Thermotogae > Petrotogales > Petrotogaceae > Petrotoga
Accessions
- Primary accessionA0A4R8EUR4
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Monomer.
Structure
Sequence
- Sequence statusComplete
- Length655
- Mass (Da)71,655
- Last updated2019-07-31 v1
- Checksum6491FB249ED95064
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
SODZ01000003 EMBL· GenBank· DDBJ | TDX16334.1 EMBL· GenBank· DDBJ | Genomic DNA |