A0A4R5LE92 · A0A4R5LE92_9BURK
- ProteinATP synthase subunit alpha
- GeneatpA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids513 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
Catalytic activity
- ATP + 4 H+(in) + H2O = ADP + 5 H+(out) + phosphate
CHEBI:30616 + 4 H+ (in)CHEBI:15378+ CHEBI:15377 = CHEBI:456216 + 5 H+ (out)CHEBI:15378+ CHEBI:43474
Features
Showing features for binding site, site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | proton-transporting ATP synthase complex, catalytic core F(1) | |
Molecular Function | ATP binding | |
Molecular Function | proton-transporting ATP synthase activity, rotational mechanism | |
Molecular Function | proton-transporting ATPase activity, rotational mechanism |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP synthase subunit alpha
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia
Accessions
- Primary accessionA0A4R5LE92
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a1, b1, b'1 and c(9-12).
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-92 | ATPase F1/V1/A1 complex alpha/beta subunit N-terminal | ||||
Sequence: VRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDIVKTTG | ||||||
Domain | 149-375 | ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding | ||||
Sequence: GLKSIDSMVPIGRGQRELIIGDRQCGKTAVAVDTIINQKGKDLICIYVAIGQKASSIQNVLRKLEETGAIEYTIVVAASASESAALQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSADYVEKFTNGEVKGKTGSLTALPIIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVS | ||||||
Domain | 382-507 | ATP synthase alpha subunit C-terminal | ||||
Sequence: QTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVALFSANNGYLDDIDVKDVLPFEKGLREYLKSKHADLVARIEDKKDLSKDDENALHAALKDF |
Sequence similarities
Belongs to the ATPase alpha/beta chains family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length513
- Mass (Da)55,870
- Last updated2019-07-31 v1
- ChecksumE768114329F17855