A0A4R0RC53 · A0A4R0RC53_9APHY
- ProteinAutophagy-related protein 2
- GeneATG2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2102 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)
- a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)
- a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | phagophore assembly site membrane | |
Molecular Function | phosphatidylinositol-3-phosphate binding | |
Biological Process | autophagosome assembly | |
Biological Process | autophagy of mitochondrion | |
Biological Process | lipid transport | |
Biological Process | piecemeal microautophagy of the nucleus | |
Biological Process | reticulophagy |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAutophagy-related protein 2
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Steccherinaceae > Steccherinum
Accessions
- Primary accessionA0A4R0RC53
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Peripheral membrane protein
Membrane ; Peripheral membrane protein
Preautophagosomal structure membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-91 | Chorein N-terminal | ||||
Sequence: TTQTLGHFVQPGQLDILQIDSQIGSGYVQIRDVELNNEAINALISGLPIQLHDGSIGKVTARIPWPNPLTSSVGLSIESLHLTFHLAA | ||||||
Region | 139-167 | Disordered | ||||
Sequence: STHLSADNVPGGLDPFVTETEETHHESEP | ||||||
Region | 270-298 | Disordered | ||||
Sequence: PSSRTASMPQQSPPTVSPSIPASPSSDID | ||||||
Region | 350-376 | Disordered | ||||
Sequence: PVPAQRSHHEEDPPVAPEASPLPPVYP | ||||||
Region | 415-445 | Disordered | ||||
Sequence: RAMSPAAADTIPPRSTEEDSGRTNTDRPGRT | ||||||
Compositional bias | 429-445 | Basic and acidic residues | ||||
Sequence: STEEDSGRTNTDRPGRT | ||||||
Region | 653-731 | Disordered | ||||
Sequence: PQSTRITHWRSRVPPGRSHVQTQSPVLSRSPGKGSPRSPRSLGGKQGQMQRVEHPAVKVKMTIVNPKPNSSSRSRRHLP | ||||||
Compositional bias | 668-697 | Polar residues | ||||
Sequence: GRSHVQTQSPVLSRSPGKGSPRSPRSLGGK | ||||||
Compositional bias | 716-730 | Polar residues | ||||
Sequence: VNPKPNSSSRSRRHL | ||||||
Region | 777-822 | Disordered | ||||
Sequence: STTPDTSTRDEYLDDSEEEDEDATPPGSPRANDLFKRTHNRDHERE | ||||||
Region | 845-868 | Disordered | ||||
Sequence: PERRSSDTTHQPRVRRKRKPKTGP | ||||||
Region | 1063-1084 | Disordered | ||||
Sequence: SDAPVYDDGDDDATERRSSKDP | ||||||
Domain | 1221-1607 | Autophagy-related protein 2 middle RBG module | ||||
Sequence: KETKVKVTLCGLTYNFHPGIAWITDLTNFVKAPPGAFETVVPSERTHISVKITDTSIRAFGAQYSGSVVLYLGEADFGTTIVGNSPQTSLRLGVTSLALYLTDDVSTLSEVTSSSRTPANVGGVLWKREGYALLAELATFTLQFSRDASLTPPDVKVSIDQGELRLHLCADTATALTAFIQDIAAAFTPPVNPEAPPKKVERKVPTSVGAHMASSHLMASLDENAFARAPDLISAPDMIQDDLPTNLDYLDESFGAAAGLRELTDDDLDEFGFGDVGDRNDPDGLVSQYGGETVRILHPQGLQIVEHHFDTLPPDTDDDAPQSNGSTFKLKVRQLDATLFLYDGYDWARTRRIIEEERKNMRRRLAKIRQLVASGQTPDPSVEETNT | ||||||
Compositional bias | 1640-1669 | Polar residues | ||||
Sequence: DQETASQSSWQSFIPPPTSPKSTASGGASK | ||||||
Region | 1640-1683 | Disordered | ||||
Sequence: DQETASQSSWQSFIPPPTSPKSTASGGASKAASGHTARVKVSKR | ||||||
Domain | 2005-2100 | Atg2/VPS13 C-terminal | ||||
Sequence: ISRYADQPTNVSEGVQSAYQSLRRNLNSAAQTILAVPMEVYERSGNEGTVRAVVRAVPIAVLKPMIGASEAISKTLLGLHNTLDPGVRMENEAKYK |
Sequence similarities
Belongs to the ATG2 family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,102
- Mass (Da)229,531
- Last updated2019-07-31 v1
- Checksum1EC83D8E85DAC4C3
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 429-445 | Basic and acidic residues | ||||
Sequence: STEEDSGRTNTDRPGRT | ||||||
Compositional bias | 668-697 | Polar residues | ||||
Sequence: GRSHVQTQSPVLSRSPGKGSPRSPRSLGGK | ||||||
Compositional bias | 716-730 | Polar residues | ||||
Sequence: VNPKPNSSSRSRRHL | ||||||
Compositional bias | 1640-1669 | Polar residues | ||||
Sequence: DQETASQSSWQSFIPPPTSPKSTASGGASK |
Keywords
- Technical term