A0A4R0R479 · A0A4R0R479_9APHY

  • Protein
    Histone acetyltransferase type B catalytic subunit
  • Gene
    HAT1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for site, binding site, active site.

150150100150200250300350400450500
TypeIDPosition(s)Description
Site227Interaction with histone H4 N-terminus
Binding site272-274acetyl-CoA (UniProtKB | ChEBI)
Binding site279-285acetyl-CoA (UniProtKB | ChEBI)
Active site307Proton donor/acceptor
Binding site319acetyl-CoA (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchromosome, telomeric region
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular Functionhistone binding
Molecular Functionhistone H4 acetyltransferase activity
Biological Processsubtelomeric heterochromatin formation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histone acetyltransferase type B catalytic subunit
  • EC number

Gene names

    • Name
      HAT1
    • ORF names
      EIP91_009528

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LE-BIN_3174
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Steccherinaceae > Steccherinum

Accessions

  • Primary accession
    A0A4R0R479

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain70-215Histone acetyl transferase HAT1 N-terminal
Region74-76Interaction with histone H4 N-terminus
Region256-258Interaction with histone H4 N-terminus
Region339-410Disordered

Sequence similarities

Belongs to the HAT1 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    501
  • Mass (Da)
    57,309
  • Last updated
    2019-07-31 v1
  • Checksum
    09B178F1B9C8EE3D
MAAAPAPDAEWVTDANESFHLSLVRPKEDKACLTAREVYEGFNPTFTYPVRVAHPPPNDPVLNRAVSPAQIFGEDEKFYGYKDLVVDLKFASGSLAQYVKISYADKLPSSSAVDNIEDTLAQFIPPGYYKSEAEFTKRVEEDATTFKPYGTLIHSYSRSARKMSSGRKNASLPQPVYNPNDDEIVEFEVYHAKWDTPGFREYHRRMQIFILLYIEGGSYIEEGEDAWEFVVLYEKRRRRSSPDVVTYHFVGYSTLYPFYCFPEKTRMRLSQFVILPPYQQEGHGSALYASIYQYIVSEPTIAELTVEDPAEPFEDLRDRNDLKMLLNNERFMREALGDDFTNSGRASPAHHPSPLLNGNGHNGHGGGGGGGGRVARSRTTHHERSVPLGSNGHGGAGASARRKTLGKMGPPVDRKWMEKWRVELKIAQRQFNRLIEMLILKHMNHADGPAFKQYRLQVKQRLYRFNYEILMQLDLEERQKKLDETFQGVKKDYDRILQTVH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RWJN01000545
EMBL· GenBank· DDBJ
TCD60783.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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