A0A4Q8N2B9 · A0A4Q8N2B9_9STAP

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site19ATP (UniProtKB | ChEBI)
Binding site67ATP (UniProtKB | ChEBI)
Binding site95ATP (UniProtKB | ChEBI)
Binding site101ATP (UniProtKB | ChEBI)
Binding site112ATP (UniProtKB | ChEBI)
Binding site122ATP (UniProtKB | ChEBI)
Active site125Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • ORF names
      DMB77_04250

Organism names

Accessions

  • Primary accession
    A0A4Q8N2B9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-148Nucleoside diphosphate kinase-like

Sequence similarities

Belongs to the NDK family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    159
  • Mass (Da)
    17,772
  • Last updated
    2019-07-31 v1
  • Checksum
    39C86292527D95C2
MKHTHRGTHIVERTFLIIKPDAVQRNLIGEIVTRIEKKGLKLVGGKLMQVPKELAEKHYSEHEGKPFYDKLISFITSAPVFAMVVEGENAVAVSRHIIGSTNPSEAAPGTIRGDLGLTLGRNIIHGSDSVESAQREVKLWFNSNEIADYLAPREDWLYE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QHKC01000001
EMBL· GenBank· DDBJ
TAA94724.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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