A0A4Q5E3T5 · A0A4Q5E3T5_BACUN

  • Protein
    ATP-dependent dethiobiotin synthetase BioD
  • Gene
    bioD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site15-20ATP (UniProtKB | ChEBI)
Binding site19Mg2+ (UniProtKB | ChEBI)
Active site40
Binding site44substrate
Binding site52ATP (UniProtKB | ChEBI)
Binding site52Mg2+ (UniProtKB | ChEBI)
Binding site117Mg2+ (UniProtKB | ChEBI)
Binding site117-120ATP (UniProtKB | ChEBI)
Binding site213ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functiondethiobiotin synthase activity
Molecular Functionmagnesium ion binding
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent dethiobiotin synthetase BioD
  • EC number
  • Alternative names
    • DTB synthetase
      (DTBS
      )
    • Dethiobiotin synthase

Gene names

    • Name
      bioD
    • ORF names
      GAP41_16990

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BIOML-A6
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides

Accessions

  • Primary accession
    A0A4Q5E3T5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the dethiobiotin synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    215
  • Mass (Da)
    24,473
  • Last updated
    2019-07-31 v1
  • Checksum
    52D8C5DF406DF122
METKNIYFISGIDTDAGKSYCTAWYARELMQRGLRIITQKFIQTGNTGHSEDIDLHRRLTGTGYLPEDKEGLTMPEIFSYPCSPHLAAHIDKRPIDFGKIERATRELSHRYDTVLVEGAGGLMVPLTEDFLTIDYIAEKQYPLIFVTSGKLGSINHTLLSFEAIKNRGIALDTVLYNLYPTVEDKTIQEDTMKYIKQYLSKHFPGTKFEVVPEIV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WCTM01000011
EMBL· GenBank· DDBJ
KAB4239447.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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