A0A4Q2ZV33 · A0A4Q2ZV33_9SPHI

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site98Transition state stabilizer
Active site102Proton acceptor
Binding site288Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      EOP56_12850

Organism names

Accessions

  • Primary accession
    A0A4Q2ZV33

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link247↔273Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-29Disordered
Domain135-445Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    759
  • Mass (Da)
    83,410
  • Last updated
    2019-07-31 v1
  • Checksum
    670852A319C22044
MGDSSNDIGKCPVHHGGMKNNVGGGGTKNRDWWPNQLKLNILRQHSSMSNPMDKEFDYAAAFKSLDYDAIKKDLHALMTDSQDWWPADFGHYGGLFVRMAWHSAGTYRVFDGRGGGAQGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNTISWADLMILTGNVALESMGFKTFGFAGGRADTWEADDATYWGAEDKWLGGDVRYTHGSEGVARHSVLVSDDDADGDKHSRNLQKPLAAVQMGLIYVNPEGPDGNPDPIAAAKDIRDTFGRMAMNDEETVALIAGGHTFGKTHGAASSDHVGKEPEAVDLEHQGFGWSSKYGSGKGPDTITSGLEVTWTQTPTKWSNHFFENLFGHEWELTKSPAGAHQWVAKNAEATIPDAFDSSKKHLPKMLTTDLALRFDPAYGKISRRFLENPGQFADAFARAWFKLTHRDMGPRARYLGPEVPQEELIWQDPIPAVDHALVDEKDIKELKAKILDSGLSVSQLASVAWASASTFRNSDKRGGANGARIRLAPQRYWLTNNPTQLGAVLSTLENIQKQFNDAQKGGKKVSLADLIVLGGCAAVEKAAKDAGHKVTVPFTPGRMDATQEQTDVESFGYLEPVADGFRNFRKSKSGVRTEEYLIDKAQLLSLTAPELTALVGGMRALNTNFDGSAHGILTSRPGQLTNDFFVNLLDMGTAWKAINEDKETYEGADRKSGERKWTATRADLVFGSNAELRAIAEVYGSADGKEKFVNDFVAAWDKVMNLDRFDLAAN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SEFT01000012
EMBL· GenBank· DDBJ
RYD56215.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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