A0A4Q1SJP9 · A0A4Q1SJP9_9BACT

  • Protein
    Adenosine 5'-phosphosulfate reductase
  • Gene
    cysH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site114[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site115[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site200[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site203[4Fe-4S] cluster (UniProtKB | ChEBI)
Active site225Nucleophile; cysteine thiosulfonate intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionadenylyl-sulfate reductase (thioredoxin) activity
Molecular Functionmetal ion binding
Molecular Functionphosphoadenylyl-sulfate reductase (thioredoxin) activity
Biological Processsulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosine 5'-phosphosulfate reductase
  • EC number
  • Short names
    APS reductase
  • Alternative names
    • 5'-adenylylsulfate reductase
    • Thioredoxin-dependent 5'-adenylylsulfate reductase

Gene names

    • Name
      cysH
    • ORF names
      ESZ00_08535

Organism names

  • Taxonomic identifier
  • Strain
    • DHOF10
  • Taxonomic lineage
    Bacteria > Acidobacteriota > Terriglobia > Terriglobales > Acidobacteriaceae > Silvibacterium

Accessions

  • Primary accession
    A0A4Q1SJP9

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain34-205Phosphoadenosine phosphosulphate reductase

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    244
  • Mass (Da)
    27,089
  • Last updated
    2019-07-31 v1
  • Checksum
    0910F7EBA028D297
MTTTAEVVIPGLAEKIAEAQRFVRAELAGREAEAAVTSSFQAEDMVVVDLVRQVLPHVPVLFLDTGYHFRATYEYRDQMAQAWNLNLVNVLPEKTVAEQEAEFGILNQIAPDKCCGLRKVGPLFKSLDPYGLWFTGLRREQAKTRANLQVAEFFSLPTGKQLRKLSPLADWTTREVWYYAQQREIPLLPLYDLGYSSIGCEPCTSLPLSSDDPRSGRWGGHKVECGIHIQPAAPVAGPGTGVEK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SDMK01000001
EMBL· GenBank· DDBJ
RXS97888.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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