A0A4Q1SD01 · A0A4Q1SD01_9BACT
- ProteinUDP-3-O-acylglucosamine N-acyltransferase
- GenelpxD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids332 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Catalytic activity
- a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a (3R)-hydroxyacyl-[ACP] = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + holo-[ACP] + H+
Pathway
Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 243 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | N-acyltransferase activity | |
Biological Process | lipid A biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-3-O-acylglucosamine N-acyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Acidobacteriota > Terriglobia > Terriglobales > Acidobacteriaceae > Silvibacterium
Accessions
- Primary accessionA0A4Q1SD01
Proteomes
Interaction
Subunit
Homotrimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 24-92 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region | |||
Sequence similarities
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length332
- Mass (Da)34,588
- Last updated2019-07-31 v1
- ChecksumE690F311CB11DB20
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
SDMK01000002 EMBL· GenBank· DDBJ | RXS94973.1 EMBL· GenBank· DDBJ | Genomic DNA |