A0A4Q1SA83 · A0A4Q1SA83_9BACT
- ProteinCytochrome c oxidase subunit 2
- GenecoxB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids345 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Catalytic activity
- 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out)
4 RHEA-COMP:10350 + CHEBI:15379 + 8 H+ (in)CHEBI:15378= 4 RHEA-COMP:14399 + 2 CHEBI:15377 + 4 H+ (out)CHEBI:15378
Cofactor
Note: Binds a copper A center.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | copper ion binding | |
Molecular Function | cytochrome-c oxidase activity | |
Molecular Function | heme binding | |
Biological Process | ATP synthesis coupled electron transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytochrome c oxidase subunit 2
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Acidobacteriota > Terriglobia > Terriglobales > Acidobacteriaceae > Silvibacterium
Accessions
- Primary accessionA0A4Q1SA83
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 50-76 | Helical | ||||
Sequence: SYFVLEITGAIFLVVGGLMAFVCFRYR | ||||||
Transmembrane | 97-119 | Helical | ||||
Sequence: LAWTVIPVLIVVVLFLTTARMIF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-26 | |||||
Sequence: MLRLWKLRKGVVAALLLLFGTALALA | ||||||
Chain | PRO_5020582256 | 27-345 | Cytochrome c oxidase subunit 2 | |||
Sequence: EGPQATPSIYAPASTPAAQIQSLSYFVLEITGAIFLVVGGLMAFVCFRYRAGKNDDKSEPAQIYGSTQVELAWTVIPVLIVVVLFLTTARMIFAIQDAPKPKEAVDVTVVGHQFWWEYRYPQLGIVTANELHIPLSSKTDPKPTYFKLLSADVDHSYWVPQLSGKTDLIPNHPNELWMDPLYPGLYKGQCAQFCGAEHALMLLRVYVDTPEQFQAWVANQQKPGVQDPTVAAGRQVFETQACMNCHAVAGTAATGRYGPDLTHLASRDTLASGVIENNPKNLRQWIKDPDSIKPGALMPAMKLSDEQLDQLTAYLATLK |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 27-125 | Cytochrome oxidase subunit II transmembrane region profile | ||||
Sequence: EGPQATPSIYAPASTPAAQIQSLSYFVLEITGAIFLVVGGLMAFVCFRYRAGKNDDKSEPAQIYGSTQVELAWTVIPVLIVVVLFLTTARMIFAIQDAP | ||||||
Domain | 128-245 | Cytochrome oxidase subunit II copper A binding | ||||
Sequence: KEAVDVTVVGHQFWWEYRYPQLGIVTANELHIPLSSKTDPKPTYFKLLSADVDHSYWVPQLSGKTDLIPNHPNELWMDPLYPGLYKGQCAQFCGAEHALMLLRVYVDTPEQFQAWVAN | ||||||
Domain | 254-345 | Cytochrome c | ||||
Sequence: PTVAAGRQVFETQACMNCHAVAGTAATGRYGPDLTHLASRDTLASGVIENNPKNLRQWIKDPDSIKPGALMPAMKLSDEQLDQLTAYLATLK |
Sequence similarities
Belongs to the cytochrome c oxidase subunit 2 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length345
- Mass (Da)37,999
- Last updated2019-07-31 v1
- ChecksumF427DC25E63EC376
Keywords
- Technical term