A0A4P8EGY5 · A0A4P8EGY5_9RHOB

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu2+ (UniProtKB | Rhea| CHEBI:29036 )

Note: Binds 1 copper ion per subunit, denoted as copper B.
heme b (UniProtKB | Rhea| CHEBI:60344 )

heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups per subunit, denoted as high- and low-spin.

Pathway

Energy metabolism; oxidative phosphorylation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site116Fe (UniProtKB | ChEBI) of heme b 1; low-spin (UniProtKB | ChEBI); axial binding residue
Binding site265Cu cation B (UniProtKB | ChEBI)
Binding site315Cu cation B (UniProtKB | ChEBI)
Binding site316Cu cation B (UniProtKB | ChEBI)
Binding site403Fe (UniProtKB | ChEBI) of heme b 2; high-spin (UniProtKB | ChEBI); axial binding residue
Binding site405Fe (UniProtKB | ChEBI) of heme b 1; low-spin (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncytochrome-c oxidase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processelectron transport coupled proton transport
Biological Processoxidative phosphorylation
Biological Processrespiratory electron transport chain

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    cytochrome-c oxidase
  • EC number

Gene names

    • Name
      ccoN
    • ORF names
      EOK75_09760

Organism names

  • Taxonomic identifier
  • Strain
    • S12M18
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Pseudorhodobacter

Accessions

  • Primary accession
    A0A4P8EGY5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-48Helical
Transmembrane68-95Helical
Transmembrane115-137Helical
Transmembrane149-172Helical
Transmembrane188-206Helical
Transmembrane218-242Helical
Transmembrane262-283Helical
Transmembrane295-312Helical
Transmembrane332-352Helical
Transmembrane364-380Helical
Transmembrane400-423Helical
Transmembrane443-463Helical
Transmembrane492-514Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-533Cytochrome oxidase subunit I profile

Sequence similarities

Belongs to the heme-copper respiratory oxidase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    533
  • Mass (Da)
    59,682
  • Last updated
    2019-07-31 v1
  • Checksum
    A0501506EC171C34
MWDYIKLIALGVIAVLAAIAANYARDPAYMVNALTIMLAAGAVFLWTLRHADEPKAAAPQNEYFDGVVRAGVIATAVWGVVGFLVGVIIAFQLAFPVLNFEWAQGYANFGRLRPLHTSAVIFAFGGNALIATSFYVVQRTSAARLWGGNLGWFVFWGYQLFIVLAATGYLLGATQSKEYAEPEWLTDWWLTVVWLAYLAAFLGTLIKRKEPHIYVANWFYLAFIITVAMLHVFNNLSIPVSMFGSKSVQVFSGVQDAMVQWWYGHNAVGFFLTAGFLGMMYYFVPKQAERPVFSYKLSIIHFWALIFLYIWAGPHHLHYTALPDWASTLGMVFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPIIRMMVVSIGFYGMSTFEGPMMSIKAVNSLSHYTDWTIGHVHSGALGWNGMITFGALYYLTPKLWNREGLYSLKLVSWHFWLATIGIVLYASSMWVTGIMEGLMWREVDANGFLVNAFADTVVAKFPMLVVRGLGGVMFLTGALIMCYNLWMTVKAQPERASDNAFVPAE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP039964
EMBL· GenBank· DDBJ
QCO56002.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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