A0A4P7QH60 · A0A4P7QH60_9CORY

Function

function

Cell wall formation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site17
Binding site140ATP (UniProtKB | ChEBI)
Binding site179-181ATP (UniProtKB | ChEBI)
Active site187
Binding site187-188ATP (UniProtKB | ChEBI)
Binding site217-224ATP (UniProtKB | ChEBI)
Binding site303Mg2+ 1 (UniProtKB | ChEBI)
Binding site314-315ATP (UniProtKB | ChEBI)
Binding site315Mg2+ 1 (UniProtKB | ChEBI)
Binding site315Mg2+ 2 (UniProtKB | ChEBI)
Binding site317Mg2+ 2 (UniProtKB | ChEBI)
Active site326

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionD-alanine-D-alanine ligase activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-alanine--D-alanine ligase
  • EC number
  • Alternative names
    • D-Ala-D-Ala ligase
    • D-alanylalanine synthetase

Gene names

    • Name
      ddl
    • ORF names
      CENDO_05205

Organism names

  • Taxonomic identifier
  • Strain
    • LMM-1653
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Corynebacteriaceae > Corynebacterium

Accessions

  • Primary accession
    A0A4P7QH60

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain144-348ATP-grasp

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    362
  • Mass (Da)
    38,357
  • Last updated
    2019-07-31 v1
  • Checksum
    93950572B658EE9D
MTTKTRVAVVYGGRSSEHSVSCVSAGAIMANLDRDKFEVIPIGITQEGFWTSGTTEGLEIVGDKLPVVEKVNELALSLAPETRGEFYDTVNGALFAKADVIFPVLHGPYGEDGTLQGLFELSGVPYVGAGVLASAAGMDKEYTKKLLAAEGLPVAPEVILRDRSELTEAEKALLGLPVFVKPARAGSSIGVSKVTDWSQLEGAVRLAHGADTKVLVESEITGSEVEIGVLQYPDGSLRASVPARLVGIEDSEEGFYGFETKYIDDVVSAEIPAQFDAGLVEQLQEMALEAFTALNCSGLSRVDFFVTDKGPVINEINTLPGFTPISMYPQVWAASGVGYSELLTLLIESALSHHEGPVASAD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP039247
EMBL· GenBank· DDBJ
QCB28326.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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