A0A4P6ULB2 · A0A4P6ULB2_9BURK

  • Protein
    Pyruvate dehydrogenase E1 component
  • Gene
    aceE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site243Mg2+ (UniProtKB | ChEBI)
Binding site273Mg2+ (UniProtKB | ChEBI)
Binding site275Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Name
      aceE
    • ORF names
      DW355_11650

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NS1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Hylemonella

Accessions

  • Primary accession
    A0A4P6ULB2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain114-310Transketolase N-terminal
Domain374-438Transketolase N-terminal
Domain498-713Pyruvate dehydrogenase E1 component middle
Domain726-866Transketolase-like C-terminal

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    909
  • Mass (Da)
    101,410
  • Last updated
    2019-07-31 v1
  • Checksum
    9F88F27F40EFFC3B
MSALPQNRLDAADLDSQETLEWKHALEAVIEQEGAERAHFLLEQLLEHAREHSIDMPFSATTGYVNSIEPDQEARSPGNLELEGRLRAYMRWNAMAMVVKANRLDPADGGDLGGHISSFQSLAHMFATGFNHFWHGDNTDEGGTHGGDLLYIQGHSAPGIYARAFLEGRISEEQLLNFRQEVDGKGLSSYPHPKLMPGFWQFPTVSMGLGPIMAIYQARFLKYLHARGIADTSQRKVWVFCGDGEMDEPESLGAIGLAAREKLDNLVFVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKLIWGKEWDALLARDKDGALRKLMMDTLDGDYQAFKANDGAYVRKNFFGRDPRTLEMVSHMSDQEVWNLRRGGHDAQKVYAAFHKAHTTTGGPTVLLVKTVKGYGMGKAGEGKNTAHQTKKLGADDVRYMRDRFNIPIPDSELDKVPFYKPAEDTPEMRYLHERRNALGGYLPKRRAKSSETFAVPSLDTFKAVLEPTAEGREISTTQAYVRFITQLLRDQALGPRVVPILVDEARTFGMEGLFRTVGIYNPEGQKYTPVDKDQVMYYREDKAGQILQEGINEAGGICSWIAAATSYSTNNRIMVPFYIYYSMFGLQRVGDLAWAAGDMQARGFLLGGTSGRTTLNGEGLQHEDGHSHVLASTIPNCVSYDPTFAHEVAVIIHHGLKRMVEKQDNVFFYITLLNENYAMPGLKAGTEEQIIKGMYLLQEADKKIAGKKGAPQVNLLGSGTILRESMFAKELLEKDWGVAANVWSCPSFNELARDGQDAERWNLLHPTEKARVPFVTQQLEPHGGPVIASTDYVKNYTEQIRPYLPKGRTYKVLGTDGFGRSDFRSKLREHFEVNRHYIVVAALKTLADEGTVPATKVAEAIAKYGIKADKINPLHA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP031395
EMBL· GenBank· DDBJ
QBK05314.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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