A0A4P6PGN8 · A0A4P6PGN8_9BACT

Function

function

Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

170150100150200250300350400450500550600650700
TypeIDPosition(s)Description
Binding site48ATP (UniProtKB | ChEBI)
Binding site375Mg2+ (UniProtKB | ChEBI)
Binding site405Mg2+ (UniProtKB | ChEBI)
Active site435Phosphohistidine intermediate
Binding site468ATP (UniProtKB | ChEBI)
Binding site564ATP (UniProtKB | ChEBI)
Binding site587ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentpolyphosphate kinase complex
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpolyphosphate kinase activity
Biological Processpolyphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyphosphate kinase
  • EC number
  • Alternative names
    • ATP-polyphosphate phosphotransferase
    • Polyphosphoric acid kinase

Gene names

    • Name
      ppk1
    • Synonyms
      ppk
    • ORF names
      EGM51_06535

Organism names

Accessions

  • Primary accession
    A0A4P6PGN8

Proteomes

Subcellular Location

PTM/Processing

Post-translational modification

An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-114Polyphosphate kinase N-terminal
Domain124-304Polyphosphate kinase middle
Domain335-496Polyphosphate kinase C-terminal
Domain505-669Polyphosphate kinase C-terminal

Sequence similarities

Belongs to the polyphosphate kinase 1 (PPK1) family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    701
  • Mass (Da)
    79,331
  • Last updated
    2019-07-31 v1
  • Checksum
    B9CA9AF9BD41B8EE
MAKTAPIPEYFNRELSWLEFNQRVLEQAKDPGSPVLERLKFLAITASNLDEFFMVRVGGLSMARKAGLRKKDPAGMTPLAQLKEIYPRSRKMMGELHRCFNDAVSPALQEGGIRHADLHAMTAEQDTFLFELFKEELFPVITPVALRDGQSVPMIQNLALNVLVRMQRRGSRDRKNLYAVMSLDRVGSRMVQLPSDEGYVYVLREEVVKKYAADWFPGYDIRESAVFRITRNADFAVAENEAPDLMRGMEDVLEERKTGDCIRLEVESSVSKGLLNFLSTSLQVAAEATFPVDGVLNMKDFMSLAFIPGYDELKVEPWPPQASPDVIPNEPMSGQIAKKDLLFYHPYETFDPVVRFIEEAAIDPDTMAIKMVLYRTSSDSAIIAALKRAAEHGVNVTVLMELKARFDEAQNISWSRTLEQCGVQVIYGVKGYKTHAKICMVVRREPAGVVRYCHFGTGNYNESTARLYSDISYMTCNPDLGNDASGFFNALCGYAQPRDFSLISMAPISMRDKLLELIDFEIERAKKGKKALVNAKVNSLVDVTLSEKLYEAANAGVKISLNIRGICCLKPIPNITVTSIIDRYLEHARIIHFHHGGKPRVYISSADWMPRNLDKRLELMVPVEDPDCRDRLIRILDIHRSDNQSAWELKPSGIYERVIKRGAKKIRSQELLYKNACAALADAEKKRRTRFEPHRPESQSI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP036201
EMBL· GenBank· DDBJ
QBG47066.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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