A0A4P6KCZ1 · A0A4P6KCZ1_9MICO

  • Protein
    Isopentenyl-diphosphate delta-isomerase
  • Gene
    fni
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

NADPH (UniProtKB | Rhea| CHEBI:57783 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site12-13substrate
Binding site70-72FMN (UniProtKB | ChEBI)
Binding site100FMN (UniProtKB | ChEBI)
Binding site129FMN (UniProtKB | ChEBI)
Binding site159substrate
Binding site160Mg2+ (UniProtKB | ChEBI)
Binding site191FMN (UniProtKB | ChEBI)
Binding site216FMN (UniProtKB | ChEBI)
Binding site221FMN (UniProtKB | ChEBI)
Binding site271-273FMN (UniProtKB | ChEBI)
Binding site292-293FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionFMN binding
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmagnesium ion binding
Molecular FunctionNADPH binding
Molecular Functionoxidoreductase activity
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • Isopentenyl diphosphate:dimethylallyl diphosphate isomerase
    • Isopentenyl pyrophosphate isomerase
    • Type 2 isopentenyl diphosphate isomerase
      (IDI-2
      )

Gene names

    • Name
      fni
    • ORF names
      EVS81_04300

Organism names

  • Taxonomic identifier
  • Strain
    • JW-1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Leucobacter

Accessions

  • Primary accession
    A0A4P6KCZ1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer. Dimer of tetramers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain166-336FMN-dependent dehydrogenase

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    364
  • Mass (Da)
    38,302
  • Last updated
    2019-07-31 v1
  • Checksum
    090980A0BC40316E
MEAPVNSERASRKDDHVRLAHEQRGDAPGANAFDDVEFVHHALAGVDASRVDLAVRVGEWRWSTPFYANGMTGGTEWTTRINRELAIAARETGMPMACGSVSVALDHPEAARGFAVIREENPTGFVMANLGVGRSADDAVRAVELLHADALQLHLNAVQETAMPEGTRDFSCWEASVERVVAASPVPVIVKEVGFGLSRRTLLRLSELGVRIADVSGAGGTDFLRIENARHDSDARRSGHDFSMLSGFGQSALACLLDAPEGGPALLASGGVRNPFDVVKALAAGAGAVGVAGSFLEALLDGGAETLVPLIERWVAQTTAILALLGAAAPAELTSTDLLVRGRLAEFCRLRGIDLTALATRSGP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP035806
EMBL· GenBank· DDBJ
QBE48147.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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