A0A4D6XYI2 · A0A4D6XYI2_9GAMM

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site73Proton acceptor
Binding site73-74NAD+ (UniProtKB | ChEBI)
Binding site147-148NAD+ (UniProtKB | ChEBI)
Binding site158NAD+ (UniProtKB | ChEBI)
Binding site175NAD+ (UniProtKB | ChEBI)
Binding site177NAD+ (UniProtKB | ChEBI)
Binding site188-193NAD+ (UniProtKB | ChEBI)
Binding site247NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      D9V72_00930

Organism names

Accessions

  • Primary accession
    A0A4D6XYI2

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    292
  • Mass (Da)
    32,497
  • Last updated
    2019-07-31 v1
  • Checksum
    779AA150E23EF964
MKQHFTCIGIVGRPRHASALITHKTLYKWLIKNGYKVFIEYTVAKELKLNNPHTATLIEIGESCDLAVVIGGDGNLLCAARVLSLYNIKIIGINRGNLGFLTDLNPDTGLKNLSKVLSGDYLLENRFLLDAQVCQKKIISRSSIAINEVVLHAKHLAHMIEFEVYIDNKFSFSQRADGLIVSTPTGSTGYSLSAGGPIIAASLDAIVLVPMFPHTLSARPLVIHSDSIICLKFSNIQTNLKISCDSQTILTIKKDECVFIRKSCYYLNLVHPKSYNYFKTLTSKLSWSKKFF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP034867
EMBL· GenBank· DDBJ
QCI22642.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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