A0A4D6QJL4 · A0A4D6QJL4_HETFO
- ProteinCatalase
- Genecat
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids526 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the degradation of hydrogen peroxide (H2O2) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.
Catalytic activity
- 2 H2O2 = O2 + 2 H2O
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 75 | ||||
Active site | 148 | ||||
Binding site | 358 | Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | peroxisomal matrix | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to hydrogen peroxide |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCatalase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Siluriformes > Heteropneustidae > Heteropneustes
Accessions
- Primary accessionA0A4D6QJL4
Subcellular Location
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-20 | Basic and acidic residues | |||
Region | 1-44 | Disordered | |||
Domain | 28-413 | Catalase core | |||
Sequence similarities
Belongs to the catalase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length526
- Mass (Da)59,837
- Last updated2019-07-03 v1
- Checksum4206A8C5924E790F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-20 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MH938564 EMBL· GenBank· DDBJ | QCF47162.1 EMBL· GenBank· DDBJ | mRNA |