A0A4D6QJL4 · A0A4D6QJL4_HETFO

Function

function

Catalyzes the degradation of hydrogen peroxide (H2O2) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
NADP+ (UniProtKB | Rhea| CHEBI:58349 )

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for active site, binding site.

152650100150200250300350400450500
Type
IDPosition(s)Description
Active site75
Active site148
Binding site358Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentperoxisomal matrix
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to hydrogen peroxide

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase
  • EC number

Gene names

    • Name
      cat

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Siluriformes > Heteropneustidae > Heteropneustes

Accessions

  • Primary accession
    A0A4D6QJL4

Subcellular Location

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-20Basic and acidic residues
Region1-44Disordered
Domain28-413Catalase core

Sequence similarities

Belongs to the catalase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    526
  • Mass (Da)
    59,837
  • Last updated
    2019-07-03 v1
  • Checksum
    4206A8C5924E790F
MAENRGKATDQMKLWKESRGSQRPDTMTTGAGVPVGDKLNVQTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYCKAKVFEHVGKTTPLAVRFSTVAGESGSADTVRDPRGFALKFYTEEGNWDLTGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGLPDGFRHMNGYGSHTFKLINSEGNPVYCKFHYKTDQGIKNLPVEEADRLASTDPDYAIRDLYNAIANGNFPSWTFYIQVMTFQQAEKYPWNPFDLTKIWSHKDYPLIPVGRFVLNKNPVNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYRARVANYQRDGPMCMTDNQGGAPNYFPNSFSAPDCQPRFMESKFRVSPDVARYNSSDEDNVTQVRTFFTKVLNDAERERLCQNMAGHLKGAQLFIQKRMVQRLMEVHQDYGSRVQALLDKYNAEGKKNSVHVYTQGGSSAVVASSKM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-20Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH938564
EMBL· GenBank· DDBJ
QCF47162.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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