A0A4D6P1T6 · A0A4D6P1T6_9CALI

  • Protein
    Genome polyprotein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Organism
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

function

Displays NTPase activity, but no helicase activity (By similarity).
Induces the formation of convoluted membranes derived from the host ER (By similarity).
These remodeled membranes probably form the viral factories that contain the replication complex (By similarity).
Together with NS2 and NS4, initiates the formation of the replication complex
Probable key protein responsible for the formation of membrane alterations by the virus (By similarity).
Induces the formation of convoluted membranes derived from the host ER (By similarity).
These remodeled membranes probably form the viral factories that contain the replication complex (By similarity).
Together with NS2 and NTPase, initiates the formation of the replication complex
Together with NTPase and NS4, initiates the formation of the replication complex (By similarity).
Induces the proliferation of the host smooth ER membranes forming long tubular structures (By similarity).
These remodeled membranes probably form the viral factories that contain the replication complex

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell cytoplasm
Cellular Componentviral capsid
Molecular FunctionATP binding
Molecular Functioncysteine-type endopeptidase activity
Molecular Functionribonucleoside triphosphate phosphatase activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Molecular FunctionRNA-dependent RNA polymerase activity
Biological ProcessDNA-templated transcription
Biological Processproteolysis
Biological Processviral RNA genome replication

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Genome polyprotein

Organism names

  • Taxonomic identifier
  • Organism
    Sapovirus GI
  • Strain
    • Hu/BRA/2014/GI.2/TO-89
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Pisuviricota > Pisoniviricetes > Picornavirales > Caliciviridae > Sapovirus > Sapporo virus

Accessions

  • Primary accession
    A0A4D6P1T6

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain452-607SF3 helicase
Domain1054-1202Peptidase C24
Domain1442-1567RdRp catalytic

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,290
  • Mass (Da)
    253,227
  • Last updated
    2019-07-03 v1
  • Checksum
    98E661019B477BE4
MASKPYRPISLDPTFEWVVFRRCYLRVAPRETFVEDFKELEHYFTTRLCAWLKRVTRTLPGREFVEEGLLDAFNSKPVVEPNEDILFRELFGVDLQEQFPMSIHDLAKLQGEAVDALRNPGHQLRRKYTTEVLQKLVTKITRVVPVQATLQDMHERRDFERERADLFKELPLLDEEITQKPKTYFYSMWRQVVKKSKAYFMPLVKTNGWVSKITKITDPIKDFIIAFCQAVQQEMGTDPRYLQLAWIQKLKPTVLTIILQQHKNTVSGWLATLTALVEVYSNLFDDLRKSAVTIISALSAFFDVCKDFIASVVDLIKTTFTPQGPTDLGWTAVMAGAVMILLKASGCPGVSGMWGKILKVCGGITTITAAIRGIKWLRELYEEAESKRLAKMYMARAAALIELAASREVTGVKELKELLSCFTVLIEEGAELLQKFGTSPLSGLIRTYVSELETQANNIRSTIMLDTPRDVPVVIILTGPPGIGKTRLAQFIGEKFGKVSNFSVAVDHHDGYTGNPVCIWDEFDVDAKGSFVETMIGIANTAPFPLNCDRVENKGRVFTSNYVICTSNYPTSVIPENPRAPAFYRRVIILDVSSPELDEWKKKNPGKKPPSDLYKQDFSHLKLMLRPYLGYNPEGDTLDGTRVKPTQISIPSLISLMQKRFKEQSGENQNLWMQVPRGAVDQASNMIKTFVYANRGVCDVIPNPASRDITETSVSKIFVSSTAPPPEFLGRHVVITGFELGDASIANSLLSMFSTSTRLTAGAQREYMYRIWNPIIHIQERSINTQNLPYVNRVIPVTSHWDFLRGLRHHLGLVSIPGMWRAFQGWRSSQGIIDFVANHMNEVTFPSNPECTVFRTGDGDVVFYTYGSYACFASPARVPYVGNPPSTIHSNVPRCMTWGETIGYLCEVVAEFTLHFGPLILAATNIAYLCSRGNREEEAKGKTKHGRGAKHAHRSSVSLSDDEYDEWRDLVRDWRKDMTVNDFLMLRERSALGMDDEDVARYRAWLEIRAMRLAGGAYTHATVIGKGGVREEIIRTAPRRAPMSVRRANYEEEAPTPIVEFTHEGDHIGYGVHLGNGRVVTVTHVASSSDSVEGAPFKVQRTVGETTWIETQLSNYPHLQIGSGRPVYYTMRLHPVVTITEGTFETPNITVHGFHVRITNGYQTRKGDCGLPYLNANRQVVGLHAGTDVQGETKLAQKVVKELPVESEFQWKGLPVIKSDLDVGGMPTGTRYHRSPAWPEQLPEETYAPAPFGAGDKRYHFSQTEMLVNALKPYTETTPGIPPSLLSRATTHVRAYLETIIGTHRSPVLTFTQAVELLEKSTSCGPFIQGLKGDYWDDETQQYTGALREHLDKAWDHAVRGIAPGNSYKLALKDELRPEEKNKEGKRRLLWGCDAATTLIAVAAFKPVAARLQVVTPMTPISVGINMDSMQMQVMNDSLRGGVLYCLDYSKWDSTQNPAVTAASLSILERFMETSPLVSCAIESLSSPAIGYLNDIKFVTKGGLPSGMPFTSVINSVNHMIYFAAGVLKAYEDHHVPYTGNVFQIETVHTYGDDCIYSVCPATASIFGSVLANLSSFGLKPTAADKTAEIKPTQTPVFLKRTFAQTPYGVRALLDINSIIRQFYWVKANRTSDPSSPPAFDRTARSAQLEAALAYASQHGPLVFDKVRDIAIKTAEGEGVVLVNTNFDLALATYNAWFIGGTAPDPERPTEGAPKLVFEMEGNGSQLPTNQNGGHVVQDVDPPGATGPTTSHVVVSNPEQPNGPAQRLEMAVATGSIQSNVPEAIRNCFAVCRTFAWNDRMPTGTFLGSLSLHPNINPYTSHLSGMWAGWGGSFEARVSISGSGMFAGRIIASIIPPGVDPTSIRDPGVLPHAFVDARVTDPVSFMIPDVRNIDYHRMDITEPTCSLGFWVYQPLLNPFATTAVTTCWVSIETKPGGDFDFCLLRPPGQQMENGVSPEGLLPRRLGYTRGNRVGGLVVGMVLVADHRQVNRHFNAQSITYGWSTAPVNPMAAAIQVNHDYTGNNNSNKRNAWLSLSAENKGPLFPGIPNHFPDSCASTVVGGMDTARHMPSTGVCGPAIGFQNNGDVYENETPAVMFATLNPLTGGTNDNPVALFGSINMASLAVVRTNQDTNFPTAGFANNMNVVVEMSWEMYTGSQQIQGRVTPMDGTNFVFTSSGANTLALWEERLLSYDGHQAILYSSQLERTAEYFQNDNVNIPPGSMAVFNVETNSASFQIGIRHDGYMVTGGTVGTHVALDAETRFQFVGILPLTATLAGPNGNSGRARRLFQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK250987
EMBL· GenBank· DDBJ
QCE43643.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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