A0A4D6K026 · A0A4D6K026_DROME

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular Functionguanylate cyclase activity
Molecular Functionpeptide receptor activity
Biological ProcesscGMP biosynthetic process
Biological Processintracellular signal transduction
Biological Processprotein phosphorylation
Biological Processreceptor guanylyl cyclase signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Guanylate cyclase
  • EC number

Gene names

    • Name
      Gucy2d
    • Synonyms
      CG12584
      , CG12585
      , CG14652
      , cg34357
      , CG41467
      , CG9783
      , Dmel\CG34357
      , GYC
    • ORF names
      CG34357
      , Dmel_CG34357

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    A0A4D6K026

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane644-668Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_502003270229-1689Guanylate cyclase

Keywords

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain, coiled coil.

TypeIDPosition(s)Description
Region102-160Disordered
Compositional bias127-160Polar residues
Region246-300Disordered
Compositional bias259-300Basic and acidic residues
Domain741-1038Protein kinase
Coiled coil1047-1074
Domain1110-1239Guanylate cyclase
Region1293-1428Disordered
Compositional bias1309-1341Polar residues
Compositional bias1354-1428Polar residues
Compositional bias1515-1529Basic and acidic residues
Region1515-1541Disordered
Region1560-1675Disordered
Compositional bias1567-1587Polar residues
Compositional bias1598-1619Polar residues
Compositional bias1620-1638Pro residues
Compositional bias1639-1674Polar residues

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,689
  • Mass (Da)
    184,996
  • Last updated
    2019-07-03 v1
  • Checksum
    D7D41BA4D5740978
MKLTTCQIAKVFPLLTAFFFLNSPSAASLSFGLSPTFASASASSSLSSSSSSSSHFHSEKPLHSDVLVLRAAKPSRAIATSADAATRSVPASAAETTLGSKSIWPTAIQTKSPRNAREAGRHKRQMQKPAIQQQPLQQQQQRINPPQQKRQQQQQQQQQVQHQAQRVGVLIPPSLHVDLTHVQQGFQNFLDFFQLHLFNVTVDFLRDVDLSGFIKLLELPKYTSVIKTLNAGIMVASHVDVDQNSTIYIGTPSQPRQQHRLHSKQEQEPHRHHHEDSKAKQFPAGEEESHSSGETEENHWNDARIFSGHCHQLAEQLALDFNKTVVLWPCPRMKISSNFLPSFEAISLAVQSISTKLNWSQVDIYIGDDNWGLGLAIAANLHVPYRIEIGRTIRDLHSQDKPGKAIIITAPLNDASTILLLSTIELDWTEQARKDGQGSRPGRQHTKILLIDMAASSLDTQHGFYKYLSRMGGSQSDAFARNTGSPAEVVSSNLLVLTLLNDRHRLFLNAAGLMATMQNFRAPLNGNYKDPPPSGHRNASLHKLYPYRNLLPLYDTIVTTTTQSDTSETSPQFDFVVLDIVRDAPVATYKWRPLLILESDPGSRGGGSVVEGGGSYISHSIHPGYDEWLLVSSVLLWQCGAICWTIAAICVCLLVIMIAGIVAGGIAMRNYFLRKRLSKGPNKIVLSASDFVFPVDSRRVDEGIEAMLCCWLQQLQEFGGPEVDKPDLLKGSIGSLKNLGFVIPGAAAPGSAGAITTTANGKSGSSATGSLARHNPAHLDMRARYNGDLVQLKEVNINGSAELRTKAMDLLVMAHGLRHENINPLIGWLSDPNRTAMVFDYCSRGSLQDVLIMDEIKLDWSFRLSLLTDLVRGMRYLHTSPLRVHGALTSRNCVVDARWVLKITDYGLNSFYESQGLPPRTRSAKELLWTAPELLRNMKLHQHHHQHGRIQLGTQLGDVYSFGIIMQEVVVRGEPYCMLSLSPEEIIVKIKKPPPLIRPSVSKGAAPPEAINIMRQCWAEQPDMRPDFNSVYERFKMLNHGRKVNFVDTMFQMLEKYSNNLEELIRERTEQLDIERKKTEQLLNRMLPSSVAEKLKMGLAVDPEEFSDVTIYFSDIVGFTTIAAHCSPVQVVDLLNDLYTIFDATINAYNVYKVETIGDAYMVVSGLPVKIPDHAEQIATMALDLLHQSGRFNVKHLPGVPLQLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGSSWRIHMSQETRDRLDARGGYAIEPRGLIDIKGKGMMNTFWLLGKKGFDKPLPAPPPIGESHGLDESLIRNSITLKAQANKSRTSTNPSSSQSSSLAGESVEVKVEITPPTNADLASGTNLPNSYSLDSNSTNTISPNATLCPEFPGKTTPSSTSPQSRKLSELTPENLLNPNSFNRLPSSTGGSSSRLYKKIEEMMDLSSPYNHYKCLSPSESNLTQFYDGKYLYGSVAGGAGGGQAGGGACASIALSGSGCGGGASRFDSKPGSSRLLRRQFSLDRDDQQAKGEQQHHQHSLQANTYSGLVGGCGGGVKSSMLDIPLLHDTTRSPKGTLTRSHKQNSASITQDLEKIEEIPLSPASSQHHSSLDSNLNRSPPSTLEAQSPPLPPMSPPQLSAPTSPAPSRTLNGIYAHNSNSTSSHGAANNNNGTHPGPELTLNAEQLLSRXGTI

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A8JQT1A8JQT1_DROMEGucy2d1685
Q0IGY5Q0IGY5_DROMEGucy2d422

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias127-160Polar residues
Compositional bias259-300Basic and acidic residues
Compositional bias1309-1341Polar residues
Compositional bias1354-1428Polar residues
Compositional bias1515-1529Basic and acidic residues
Compositional bias1567-1587Polar residues
Compositional bias1598-1619Polar residues
Compositional bias1620-1638Pro residues
Compositional bias1639-1674Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014297
EMBL· GenBank· DDBJ
QCD25197.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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