A0A4D6HIF9 · A0A4D6HIF9_9EURY
- ProteintRNA-guanine(15) transglycosylase
- GenetgtA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids493 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Catalytic activity
- guanosine15 in tRNA + 7-cyano-7-deazaguanine = 7-cyano-7-carbaguanosine15 in tRNA + guanine
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
tRNA modification; archaeosine-tRNA biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 93 | Nucleophile | |||
Binding site | 128 | substrate | |||
Binding site | 196 | substrate | |||
Binding site | 279 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 281 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 284 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | pentosyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | queuosine biosynthetic process | |
Biological Process | tRNA wobble guanine modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-guanine(15) transglycosylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Natrialbaceae > Natronorubrum
Accessions
- Primary accessionA0A4D6HIF9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length493
- Mass (Da)54,061
- Last updated2019-07-03 v1
- ChecksumE6EB17D262B315CF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP031305 EMBL· GenBank· DDBJ | QCC53663.1 EMBL· GenBank· DDBJ | Genomic DNA |