A0A499FJ16 · A0A499FJ16_HUMAN

  • Protein
    non-specific protein-tyrosine kinase
  • Gene
    TNK2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

110861002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site221ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific protein-tyrosine kinase
  • EC number

Gene names

    • Name
      TNK2

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A499FJ16

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
Cytoplasm
Endomembrane system
; Peripheral membrane protein
Nucleus

Keywords

Disease & Variants

Organism-specific databases

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)347PRIDEPhosphotyrosine
Modified residue (large scale data)595PRIDEPhosphothreonine
Modified residue (large scale data)596PRIDEPhosphotyrosine
Modified residue (large scale data)802PRIDEPhosphoserine
Modified residue (large scale data)806PRIDEPhosphoserine
Modified residue (large scale data)852PRIDEPhosphoserine
Modified residue (large scale data)863PRIDEPhosphoserine
Modified residue (large scale data)869PRIDEPhosphothreonine
Modified residue (large scale data)871PRIDEPhosphoserine
Modified residue (large scale data)905PRIDEPhosphotyrosine
Modified residue (large scale data)935PRIDEPhosphothreonine
Modified residue (large scale data)937PRIDEPhosphotyrosine
Modified residue (large scale data)938PRIDEPhosphotyrosine

Keywords

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region153-177Disordered
Domain189-448Protein kinase
Domain451-511SH3
Region559-613Disordered
Compositional bias575-591Pro residues
Region737-780Disordered
Region796-918Disordered
Compositional bias802-834Pro residues
Compositional bias850-883Pro residues
Compositional bias884-905Polar residues
Region958-1037Disordered
Compositional bias962-985Pro residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,086
  • Mass (Da)
    119,349
  • Last updated
    2019-07-03 v1
  • Checksum
    6FC37F9EFDF69D5E
MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQRLGGGRMQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVKREPPPRPPQPAFFTQKPTYDPVSEDQDPLSSDFKRLGLRKPGLPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATARLPQRGCPGDGPEAGRPADKIQMVEQLFGLGLRPRGECHKVLEMFDWNLEQAGCHLLGSWGPAHHKR

Computationally mapped potential isoform sequences

There are 19 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q07912ACK1_HUMANTNK21038
C9J1X3C9J1X3_HUMANTNK21040
A0A5F9ZH01A0A5F9ZH01_HUMANTNK2301
A0A5F9ZH66A0A5F9ZH66_HUMANTNK295
A0A5F9ZHI7A0A5F9ZHI7_HUMANTNK2143
A0A5F9ZHJ2A0A5F9ZHJ2_HUMANTNK21072
A0A5F9ZHK8A0A5F9ZHK8_HUMANTNK292
A0A5F9ZHL4A0A5F9ZHL4_HUMANTNK2289
A0A5F9ZHP4A0A5F9ZHP4_HUMANTNK21008
A0A5F9ZHP9A0A5F9ZHP9_HUMANTNK297
A0A5F9ZHQ1A0A5F9ZHQ1_HUMANTNK2154
A0A5F9ZI29A0A5F9ZI29_HUMANTNK21040
A0A5F9ZI44A0A5F9ZI44_HUMANTNK2118
A0A5F9ZGX5A0A5F9ZGX5_HUMANTNK21055
A0A5F9ZGY5A0A5F9ZGY5_HUMANTNK2153
A0A5F9ZHX6A0A5F9ZHX6_HUMANTNK2144
A0A5F9ZHB0A0A5F9ZHB0_HUMANTNK2280
A0A5F9ZHC7A0A5F9ZHC7_HUMANTNK298
A0A5F9ZHD0A0A5F9ZHD0_HUMANTNK2550

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias575-591Pro residues
Compositional bias802-834Pro residues
Compositional bias850-883Pro residues
Compositional bias884-905Polar residues
Compositional bias962-985Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC124944
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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