A0A499FJ16 · A0A499FJ16_HUMAN
- Proteinnon-specific protein-tyrosine kinase
- GeneTNK2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1086 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 221 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | intracellular membrane-bounded organelle | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | non-membrane spanning protein tyrosine kinase activity | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific protein-tyrosine kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A499FJ16
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endomembrane system ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Modified residue (large scale data) | 347 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 595 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 596 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 802 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 806 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 852 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 863 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 869 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 871 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 905 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 935 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 937 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 938 | PRIDE | Phosphotyrosine | |||
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 153-177 | Disordered | |||
Domain | 189-448 | Protein kinase | |||
Domain | 451-511 | SH3 | |||
Region | 559-613 | Disordered | |||
Compositional bias | 575-591 | Pro residues | |||
Region | 737-780 | Disordered | |||
Region | 796-918 | Disordered | |||
Compositional bias | 802-834 | Pro residues | |||
Compositional bias | 850-883 | Pro residues | |||
Compositional bias | 884-905 | Polar residues | |||
Region | 958-1037 | Disordered | |||
Compositional bias | 962-985 | Pro residues | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,086
- Mass (Da)119,349
- Last updated2019-07-03 v1
- Checksum6FC37F9EFDF69D5E
Computationally mapped potential isoform sequences
There are 19 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q07912 | ACK1_HUMAN | TNK2 | 1038 | ||
C9J1X3 | C9J1X3_HUMAN | TNK2 | 1040 | ||
A0A5F9ZH01 | A0A5F9ZH01_HUMAN | TNK2 | 301 | ||
A0A5F9ZH66 | A0A5F9ZH66_HUMAN | TNK2 | 95 | ||
A0A5F9ZHI7 | A0A5F9ZHI7_HUMAN | TNK2 | 143 | ||
A0A5F9ZHJ2 | A0A5F9ZHJ2_HUMAN | TNK2 | 1072 | ||
A0A5F9ZHK8 | A0A5F9ZHK8_HUMAN | TNK2 | 92 | ||
A0A5F9ZHL4 | A0A5F9ZHL4_HUMAN | TNK2 | 289 | ||
A0A5F9ZHP4 | A0A5F9ZHP4_HUMAN | TNK2 | 1008 | ||
A0A5F9ZHP9 | A0A5F9ZHP9_HUMAN | TNK2 | 97 | ||
A0A5F9ZHQ1 | A0A5F9ZHQ1_HUMAN | TNK2 | 154 | ||
A0A5F9ZI29 | A0A5F9ZI29_HUMAN | TNK2 | 1040 | ||
A0A5F9ZI44 | A0A5F9ZI44_HUMAN | TNK2 | 118 | ||
A0A5F9ZGX5 | A0A5F9ZGX5_HUMAN | TNK2 | 1055 | ||
A0A5F9ZGY5 | A0A5F9ZGY5_HUMAN | TNK2 | 153 | ||
A0A5F9ZHX6 | A0A5F9ZHX6_HUMAN | TNK2 | 144 | ||
A0A5F9ZHB0 | A0A5F9ZHB0_HUMAN | TNK2 | 280 | ||
A0A5F9ZHC7 | A0A5F9ZHC7_HUMAN | TNK2 | 98 | ||
A0A5F9ZHD0 | A0A5F9ZHD0_HUMAN | TNK2 | 550 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 575-591 | Pro residues | |||
Compositional bias | 802-834 | Pro residues | |||
Compositional bias | 850-883 | Pro residues | |||
Compositional bias | 884-905 | Polar residues | |||
Compositional bias | 962-985 | Pro residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC124944 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |