A0A497PNX8 · A0A497PNX8_THOAR
- ProteintRNA-splicing ligase RtcB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids144 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Essential for tRNA splicing and maturation. Acts by directly joining spliced tRNA halves to mature-sized tRNAs. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
Catalytic activity
- a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate + H+
Cofactor
Note: Binds 2 manganese ions per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA ligase activity | |
Molecular Function | GTP binding | |
Molecular Function | manganese ion binding | |
Molecular Function | RNA ligase (GTP) activity | |
Biological Process | DNA repair | |
Biological Process | RNA processing | |
Biological Process | RNA repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-splicing ligase RtcB
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Asgard group > Candidatus Thorarchaeota
Accessions
- Primary accessionA0A497PNX8
Proteomes
Interaction
Subunit
Monomer.
Structure
Sequence
- Sequence statusFragment
- Length144
- Mass (Da)15,473
- Last updated2019-06-05 v1
- ChecksumF52EB4BC344AE923
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 144 | |||||
Sequence: L |