A0A495KGS2 · A0A495KGS2_ENTAS
- ProteinProbable endonuclease 4
- Genenfo
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids285 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
Catalytic activity
Cofactor
Note: Binds 3 Zn2+ ions.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 69 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 109 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 145 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 145 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 179 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 182 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 216 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 229 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 231 | Zn2+ 3 (UniProtKB | ChEBI) | |||
Binding site | 261 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | deoxyribonuclease IV (phage-T4-induced) activity | |
Molecular Function | DNA binding | |
Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
Molecular Function | phosphoric diester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | base-excision repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable endonuclease 4
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter > Enterobacter cloacae complex
Accessions
- Primary accessionA0A495KGS2
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length285
- Mass (Da)31,390
- Last updated2019-06-05 v1
- MD5 Checksum4D699C7035306FDE317B2DDF5BF85E5E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAELXN010000065 EMBL· GenBank· DDBJ | MBJ6597552.1 EMBL· GenBank· DDBJ | Genomic DNA |