A0A493TFP0 · A0A493TFP0_ANAPP
- ProteinPOU domain, class 2, transcription factor 1
- GenePOU2F1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids735 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 371-430 | Homeobox | ||||
Sequence: RRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRIN |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended namePOU domain, class 2, transcription factor 1
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas
Accessions
- Primary accessionA0A493TFP0
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MFCVSPGQGSIDRFVCFLLVLLHLCFC | ||||||
Chain | PRO_5019776281 | 28-735 | POU domain, class 2, transcription factor 1 | |||
Sequence: FNADSRMNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQLTLTPAQQQLLLQQAQAQLLAAAVQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQHLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLASQPATPTRTIAATPIQPLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSTLSSPSALNSPGLGGEGLNRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPCPTSLVATTPSLVTSSAATTLTVNPVLPLTSPAVTSLSVTGTTETNSNNTATVISTAPPASSAVTSPSMSPSPSASASTSEASSASETSTTQTTSAPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPGLMASSQFAAGGALLSLNPGTLGGALSPALMSNSTLATIQALASGGSLPITSLDATGNLVFANAGGTPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASAGASGPVASLHATSTSAESIQNSLLTVASASGATSTTTTASKAQ |
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 36-61 | Disordered | ||||
Sequence: NPSETSKPSMESGDGNTGTQTNGLDF | ||||||
Compositional bias | 249-266 | Polar residues | ||||
Sequence: TPIQPLPQSQSTPKRIDT | ||||||
Region | 249-273 | Disordered | ||||
Sequence: TPIQPLPQSQSTPKRIDTPSLEEPS | ||||||
Domain | 270-344 | POU-specific | ||||
Sequence: EEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE | ||||||
Region | 348-374 | Disordered | ||||
Sequence: SDSTLSSPSALNSPGLGGEGLNRRRKK | ||||||
Domain | 369-429 | Homeobox | ||||
Sequence: NRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRI | ||||||
Region | 485-548 | Disordered | ||||
Sequence: SVTGTTETNSNNTATVISTAPPASSAVTSPSMSPSPSASASTSEASSASETSTTQTTSAPLSSP |
Sequence similarities
Belongs to the POU transcription factor family. Class-2 subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length735
- Mass (Da)75,873
- Last updated2019-06-05 v1
- Checksum7AD4A1C40185BC80
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A493T9V0 | A0A493T9V0_ANAPP | POU2F1 | 775 | ||
U3IEC4 | U3IEC4_ANAPP | POU2F1 | 751 | ||
A0A493TDH9 | A0A493TDH9_ANAPP | POU2F1 | 269 | ||
A0A493U0E9 | A0A493U0E9_ANAPP | POU2F1 | 752 | ||
A0A493T0D3 | A0A493T0D3_ANAPP | POU2F1 | 715 | ||
A0A493SZC8 | A0A493SZC8_ANAPP | POU2F1 | 701 | ||
A0A493SY50 | A0A493SY50_ANAPP | POU2F1 | 672 | ||
A0A493T5P1 | A0A493T5P1_ANAPP | POU2F1 | 693 | ||
A0A493THW4 | A0A493THW4_ANAPP | POU2F1 | 745 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 249-266 | Polar residues | ||||
Sequence: TPIQPLPQSQSTPKRIDT |
Keywords
- Technical term