A0A493TE53 · A0A493TE53_ANAPP

Function

Catalytic activity

Features

Showing features for binding site, active site.

140550100150200250300350400
TypeIDPosition(s)Description
Binding site142ATP (UniProtKB | ChEBI)
Binding site161ATP (UniProtKB | ChEBI)
Binding site210-212ATP (UniProtKB | ChEBI)
Active site255Proton acceptor
Binding site259-260ATP (UniProtKB | ChEBI)
Binding site273ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon hillock
Cellular Componentciliary basal body
Cellular Componentcytosol
Cellular Componentgerminal vesicle
Cellular Componentglutamatergic synapse
Cellular Componentmeiotic spindle
Cellular Componentmitotic spindle pole
Cellular Componentnucleoplasm
Cellular Componentperinuclear region of cytoplasm
Cellular Componentpostsynaptic density
Cellular Componentpronucleus
Cellular Componentspindle microtubule
Cellular Componentspindle pole centrosome
Molecular FunctionATP binding
Molecular Functionhistone H3S10 kinase activity
Molecular Functionprotein heterodimerization activity
Molecular Functionprotein kinase binding
Molecular Functionubiquitin protein ligase binding
Biological Processanterior/posterior axis specification
Biological Processapoptotic process
Biological Processcentrosome localization
Biological Processcilium disassembly
Biological Processliver regeneration
Biological Processmitotic centrosome separation
Biological Processmitotic spindle organization
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of gene expression
Biological Processneuron projection extension
Biological Processpositive regulation of mitochondrial fission
Biological Processpositive regulation of oocyte maturation
Biological Processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic process
Biological Processprotein localization to centrosome
Biological Processregulation of protein stability
Biological Processresponse to wounding
Biological Processspindle assembly involved in female meiosis I

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aurora kinase
  • EC number

Gene names

    • Name
      AURKA

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas

Accessions

  • Primary accession
    A0A493TE53

Proteomes

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link257Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region20-130Disordered
Compositional bias27-82Polar residues
Compositional bias91-113Polar residues
Compositional bias114-130Basic and acidic residues
Domain132-382Protein kinase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    405
  • Mass (Da)
    45,860
  • Last updated
    2019-06-05 v1
  • Checksum
    63379F2982C3088B
VEQEKNTCIRGVDTASAVVDGPKRVPVSQHSAQSRVLNSGGQAQRVLCPSNLAQRVPVQSQKSVPSNQKLSNNQTTQQPRPKFLVQPMARPQVPSKTNEKPQQAPAPGNSEDDAESSSKQKNEERQWSLDDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKTQLEEAGVEHQLRREVEIQSHLRHPNILRLYGYFHDVTRVYLILEYAPRGEVYKELQKLTKFDEQRTATYITELADALSYCHSKNVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRTHDEKVDIWSLGVLCYEFLVGKPPFEAATYQETYRAISRVEFKYPAFVTEGAKDLISKLLKHNPFHRMPLKDVLVHPWITANSTKLPNSRKSDVTAPPRTQS

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
U3IAE4U3IAE4_ANAPPAURKA347
A0A493T9N6A0A493T9N6_ANAPPAURKA258

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias27-82Polar residues
Compositional bias91-113Polar residues
Compositional bias114-130Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp