A0A493TAI5 · A0A493TAI5_ANAPP

Function

Catalytic activity

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.
    EC:2.3.2.27 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; protein ubiquitination.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionubiquitin protein ligase activity
Biological Processapoptotic process
Biological Processnegative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
Biological Processnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic process
Biological Processprotein K48-linked ubiquitination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RING-type E3 ubiquitin transferase
  • EC number

Gene names

    • Name
      RFFL

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas

Accessions

  • Primary accession
    A0A493TAI5

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm, cytosol

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region147-204Disordered
Domain287-322RING-type

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    334
  • Mass (Da)
    37,274
  • Last updated
    2019-06-05 v1
  • Checksum
    81A9EE9A2792EE6C
MWAGCCNWFCLDGSAEEMQSQPEQGARAQAYSNPGYSSYPSPTASEESCKACGVHFDNSSRKHICVDCKKHFCMSCSNQTEDGPLLCHLCQRFRATGFQREELMKMKVKELRDYLTLHEISTELCREKEDLVFLILSQHPVINQEDQIRTSPFNTSASGQQDFVTHPSTSTASSTSRDASPVSADSISSSRAQEHQQSTHSGDNLVLGRKASLSDLTSIGDINALSVRQLKEILARNFVNYKGCCEKWELLERVARLYKEKDLQHLVSDTDDQMGGAGRSGTEDNLCKICMDLPADCVLLECGHLVTCTKCGKRMSECPICRQYVVRAVHVFRS

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A493TF45A0A493TF45_ANAPPRFFL385
A0A493SZ40A0A493SZ40_ANAPPRFFL362
A0A493SYJ9A0A493SYJ9_ANAPPRFFL365
A0A493TNN6A0A493TNN6_ANAPPRFFL385
U3IMF6U3IMF6_ANAPPRFFL354
A0A493SWF0A0A493SWF0_ANAPPRFFL330

Keywords

Genome annotation databases

Similar Proteins

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