A0A493T008 · A0A493T008_ANAPP
- ProteinAldehyde dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids488 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (2E)-hexadecenal + H2O + NAD+ = (E)-hexadec-2-enoate + 2 H+ + NADH
- 2 H+ + hexadecanoate + NADH = H2O + hexadecanal + NAD+
- 2,6,10,14-tetramethylpentadecanal + H2O + NAD+ = 2,6,10,14-tetramethylpentadecanoate + 2 H+ + NADH
- 22-oxodocosanoate + H2O + NAD+ = docosanedioate + 2 H+ + NADH
- H2O + NAD+ + octadecanal = 2 H+ + NADH + octadecanoate
- H2O + NAD+ + octanal = 2 H+ + NADH + octanoate
- H2O + NAD+ + tetradecanal = 2 H+ + NADH + tetradecanoate
- H2O + heptanal + NAD+ = 2 H+ + heptanoate + NADH
- a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH
- decanal + H2O + NAD+ = decanoate + 2 H+ + NADH
- dodecanoate + 2 H+ + NADH = dodecanal + H2O + NAD+
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 210 | |||||
Sequence: E | ||||||
Active site | 244 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | |
Biological Process | cellular aldehyde metabolic process | |
Biological Process | fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAldehyde dehydrogenase
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas
Accessions
- Primary accessionA0A493T008
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 465-487 | Helical | ||||
Sequence: VRYGLIFLALLGVVAAVMIKVMF |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-425 | Aldehyde dehydrogenase | ||||
Sequence: RMQQVVGRARAAFSSGRCRSLEFRLQQLKNLERMVREKEKEILAALQSDLHKCGHNAYSHEVMGVLGELAQAMENLPSWAAPQPVKKNLLTMRDEAYIYPEPLGVVLVIGAWNYPFMLVVQPLIGAIAAGNAVVVKPSEVSEHTSQLLADLLPQYLDEELYPVVTGGVPETTELLKQRFDHILYTGNTAVGKIVMAAAAKHLTPVTLELGGKSPCYIDKDCDLAVACRRITWGKYMNCGQTCIAPDYILCEPSIQSQVVENIKATLQEFYGEDVKKSPDYERIVNKRHFRRIVSLLEGQKIAHGGETDEASCFIAPTILTDVSAESKVMEEEIFGPVLPIVSVKGVDEAIEFINSREKPLALYVFSNDKKLIKRVISETSSGGMTANDVLMHSTVLDLPFGGVGNSGMGAYHGKHSFETFSHH | ||||||
Coiled coil | 23-50 | |||||
Sequence: LEFRLQQLKNLERMVREKEKEILAALQS |
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length488
- Mass (Da)54,249
- Last updated2019-06-05 v1
- ChecksumF0E9B29C0215E36D
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A493U1U7 | A0A493U1U7_ANAPP | 512 | |||
U3I4K2 | U3I4K2_ANAPP | 510 | |||
A0A493T3P1 | A0A493T3P1_ANAPP | 490 | |||
U3I679 | U3I679_ANAPP | 487 |
Keywords
- Technical term