A0A486MX84 · A0A486MX84_KLEPN

  • Protein
    Chitooligosaccharide deacetylase
  • Gene
    chbG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Glycan degradation; chitin degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61Mg2+ (UniProtKB | ChEBI)
Binding site125Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionchitin disaccharide deacetylase activity
Molecular Functiondeacetylase activity
Molecular Functionmetal ion binding
Molecular Functiontransferase activity
Biological Processchitin catabolic process
Biological Processdiacetylchitobiose catabolic process
Biological Processpolysaccharide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Chitooligosaccharide deacetylase
  • EC number
  • Short names
    COD
  • Alternative names
    • Chitin disaccharide deacetylase
    • Chitobiose deacetylase
    • Chitobiose-6P deacetylase
    • Chitotriose deacetylase
    • Chitotriose-6P deacetylase

Gene names

    • Name
      chbG
    • ORF names
      LS45_18230
      , SAMEA4873561_04172
      , SAMEA4873648_00145

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • UMNturkey9
    • 5012STDY7626360
    • 5012STDY7626446
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0A486MX84

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the YdjC deacetylase family. ChbG subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    252
  • Mass (Da)
    27,685
  • Last updated
    2019-06-05 v1
  • Checksum
    3E728EE248274549
MERVLIVNADDFGLSKGQNYGIIEACRNGVVTSTTALVNGAAIDHAAQLGRSTPELAVGMHFVLTLGEPLSAMPGLTRDGRLGKWIWQQAEEDSLPLEEIAHELACQYHRFVELFGHEPTHIDSHHHVHMFAQIYPIVAAFAREKGIALRIDRQVAAQSGLDQQAARSSAGFSSEFYGEAVSEELFLQTLDASIARGERSLEVMCHPAYVDRIIMGSAYCYPRLDELDVLTAASLKAAVADRGYRLGTYRDV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JRRF01000015
EMBL· GenBank· DDBJ
KII03838.1
EMBL· GenBank· DDBJ
Genomic DNA
CAAHCS010000001
EMBL· GenBank· DDBJ
VGL40762.1
EMBL· GenBank· DDBJ
Genomic DNA
CAAHDG010000012
EMBL· GenBank· DDBJ
VGM51941.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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