A0A484DEM6 · A0A484DEM6_PERFV

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

113751002003004005006007008009001,0001,1001,2001,300
Type
IDPosition(s)Description
Binding site1071-1079ATP (UniProtKB | ChEBI)
Binding site1097ATP (UniProtKB | ChEBI)
Binding site1144-1147ATP (UniProtKB | ChEBI)
Active site1191Proton acceptor
Binding site1195ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentbasal plasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionhepatocyte growth factor receptor activity
Biological Processaxon guidance
Biological Processcell migration
Biological Processliver development
Biological Processpancreas development
Biological Processpositive regulation of kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • ORF names
      EPR50_G00038320

Organism names

  • Taxonomic identifier
  • Strain
    • YP-PL-M2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Percinae > Perca

Accessions

  • Primary accession
    A0A484DEM6

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane943-967Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, modified residue.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_501972768422-1375receptor protein-tyrosine kinase
Disulfide bond98↔101
Disulfide bond133↔141
Disulfide bond167↔170
Disulfide bond293↔360
Disulfide bond378↔399
Disulfide bond512↔530
Disulfide bond518↔552
Disulfide bond521↔537
Disulfide bond533↔543
Modified residue1221Phosphotyrosine; by autocatalysis
Modified residue1222Phosphotyrosine; by autocatalysis
Modified residue1336Phosphotyrosine; by autocatalysis
Modified residue1343Phosphotyrosine; by autocatalysis

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain24-507Sema
Domain1065-1328Protein kinase
Region1350-1375Disordered

Sequence similarities

Belongs to the plexin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,375
  • Mass (Da)
    153,106
  • Last updated
    2019-06-05 v1
  • Checksum
    6B6DCBDF291C521A
MVTWAALLTVCIWIQTQTASGQHTCASTPRRLVDFTVKYSLPHFQTDKPIQNIAVNREENQQEVYIGSQNVIEALNDAMEKIWEVKTGPVGSPDCETCRVCDIEIDPGDPVETDNEVLLLDFSAFPYPSLYICGSTQHGICHYIEVGTPEPIPKCLYKKGQNSLANCPDCLASPLGTKVTIVEEGATTLFFVAASVNDKVAQRYPRRSISVMRPLSTEDGFHMVMEGLMVLPSLRDSYTIDYIYSFSTTDYVYFLSLQRENPFKNNSAFQTRLGRQSILIPEVWMYREVVLECRYKPKRRRRRRENLSDIVYNGLQAAYFGRAGKDLADELSVTETEDILYGVFAEVNERGEPKKNSVLCAFPLSKVNDAIDKGVEACCKSGPEQLSRGLCHFQPCEGCPHESSEDNDTCSAKPTLVSKPYYRLDLFNRQMRDVLFTAVLVTTIGNYTLGHFGTSDGRILQVILTSYKPIVFANYSLGGSKVSSKAEVYSNDLLLFTVGNKMFKVPSAGPGCAHFMTCSKCLMAPRFMNCGWCSGMCLRQRECASKWNKDSCTPVITEFFPKMAPAGAETEVTLCGWEFQSPLPPAIISGKTHIITVGSGTLCTVLPEKSSSEVLVCKIQEFTPNPDLNITLEVHEGEVKGHYSIEGTAQMPGFSFVEPSITEIKPDYGPMFGGTTVTLTGRYLNSGIQRDVFFANKKCNNQSVTEGIGTSSIVCQTAAAAGVGRVPVKIVIDNFQVTTPKMFFYKKDPVITSVHPHCSFQSGSKLVIEGRNLDSAHKTVVQYTSKNPNLQSLERVCSGTTNATYMECWAPDFPEEMPEEKSDTGEIFIHMDGKSNLWKRRFDYHHNIKIIPFENEDNVLLLKPGETEVALHHSKLNTVSICMNITMTIGGVNCNAQVLSNELTCRIPKGLLIPSEGLPVEVFVNGEVHVVGTVVNNDNNNTVIVGIVLGIIAALAIGAGLALLVMIHLRKKKRANVANRQSTVLSWNRMGSSPDFVPTGDYRRVDLASQTSGSGGMAFQGLLYAANNDLSIPLMPQDNISMVSLSSDLLEEVKDVLIPAEMLRIEDSQIIGKGHFGTVYHGYLIDCNKQETHCAVKSLNRITDLGEVDQFLREGIIMKGFHHPNILSLLGIMLPKEGLPLVVLPYMKHGDVRHFIRSEKRNPTVKDLIGFGLQVAKGMEYLAQKKFVHRDLAARNCMLDETYTVKVADFGMARDIYDKEYYSIQDHKRVKLPVKWMALESLQTQKFTAKSDVWSYGILMWELLTRGANPYPNVDPYDITHYLLKGRRLAQPQFCPDTLYSIMLTCWDPEPEFRPSFNSLVTDVQNILSCLDGEHYINLKVNYVNLDQPRPYPSQTGSADEAESSDLDTDSHATS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCKG01000004
EMBL· GenBank· DDBJ
TDH13909.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help