A0A484CWB7 · A0A484CWB7_PERFV

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 3 Ca2+ ions per subunit. Two of the Ca2+ ions are bound to the C2 domain.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site304
Binding site305Ca2+ 3 (UniProtKB | ChEBI); catalytic
Binding site334Ca2+ 3 (UniProtKB | ChEBI); catalytic
Binding site336Ca2+ 3 (UniProtKB | ChEBI); catalytic
Active site349
Binding site383Ca2+ 3 (UniProtKB | ChEBI); catalytic
Binding site432substrate
Binding site434substrate
Binding site508substrate
Binding site535substrate
Binding site637Ca2+ 4 (UniProtKB | ChEBI)
Binding site639Ca2+ 4 (UniProtKB | ChEBI)
Binding site663Ca2+ 4 (UniProtKB | ChEBI)
Binding site692Ca2+ 5 (UniProtKB | ChEBI)
Binding site694Ca2+ 5 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentnucleus
Molecular Functioncalcium ion binding
Molecular Functionphosphatidylinositol phospholipase C activity
Biological Processintracellular signal transduction
Biological Processlipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoinositide phospholipase C
  • EC number

Gene names

    • ORF names
      EPR50_G00120980

Organism names

  • Taxonomic identifier
  • Strain
    • YP-PL-M2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Percinae > Perca

Accessions

  • Primary accession
    A0A484CWB7

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for glycosylation.

TypeIDPosition(s)Description
Glycosylation184O-linked (GlcNAc) serine

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain15-123PH
Domain133-168EF-hand
Domain169-204EF-hand
Region441-473Disordered
Compositional bias443-457Acidic residues
Compositional bias458-473Basic and acidic residues
Domain479-595PI-PLC Y-box
Domain595-723C2

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    744
  • Mass (Da)
    85,140
  • Last updated
    2019-06-05 v1
  • Checksum
    A893D037D491BECE
MDPEGSRIEDDPDVKVMMAGSTLKKVKSRSWKKQRHFRLLEDAVTIWYKSRWAGKGHSTFSISEVEAVREGHQSEVLQSTAEEFPAELCFTLVFHGRQGNLDLVAKTPEEAKAWIEGVRKLIHKAQTMDEKERQDQWIRDWFQKADKNKDGKMNFKEVQTLLKMMNVEMNEDHALNLFTKADKSESGSLEIEQFVHFYKMLTQRDEVWKVFQDYSGDGEKLLLEELETFLSMEQHEGGQSYQLAKMLIDRYEPSESAKKQRIMSLDGFQMYLCSQEGSIFKPKHLDLYQDMSQPLSHYFISSSHNTYLLEDQLLGQSSLEAYIKALKRGCRCVEVDCWDGSDGEPIVYHGHTFTSKILFRDVISTLKEYAFKASDFPVILSLENHCGVEQQTVMAQHLSKILGDTLLTTLLDGQVPQQLPSPQELKGKILLKAKKLNNPEDCLDETQTDEVSDEEAEDAESPTKGNPPARKKSKLSRELSDLVVYCKSVHFRDFEHARSHAKCYEISSFSENKAQARAKDEGTDFVRYNTRQLSRIYPDGLRTNSSNYNPQEMWNVGCQIVALNFQTAGLEMDLNDGLFRQNGCCGYVLKPDFMRDGNTQFSPDKPEERQGYKPLRLSIQVISGQQLPKVNQKEGSIVDPLVRVQIFGVPGDQDMKETPYINNNGFNPVWDETLNFVIHTPELALVRFEVEDHDRASRNDFIGQFTLPFMCIQAGYRHIHLLSKDGIAIPPASLFVNISISELP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias443-457Acidic residues
Compositional bias458-473Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCKG01000011
EMBL· GenBank· DDBJ
TDH07199.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp