A0A484CVY3 · A0A484CVY3_PERFV

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (2E)-hexadecenedioyl-CoA + H2O = (3S)-hydroxyhexadecanedioyl-CoA
    This reaction proceeds in the forward direction.
  • (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA = (2E)-2-methylbut-2-enoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • (3E)-decenoyl-CoA = (2E)-decenoyl-CoA
    This reaction proceeds in the forward direction.
  • (3E)-hexenoyl-CoA = (2E)-hexenoyl-CoA
    This reaction proceeds in the forward direction.
  • (3E,5Z)-octadienoyl-CoA = (2E,5Z)-octadienoyl-CoA
    This reaction proceeds in the backward direction.
  • (3E,5Z)-tetradecadienoyl-CoA = (2E,5Z)-tetradecadienoyl-CoA
    This reaction proceeds in the backward direction.
  • (3S)-hydroxydecanoyl-CoA + NAD+ = 3-oxodecanoyl-CoA + H+ + NADH
    This reaction proceeds in the forward direction.
  • (3S)-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • (3S)-hydroxyhexadecanedioyl-CoA + NAD+ = 3-oxohexadecanedioyl-CoA + H+ + NADH
    This reaction proceeds in the forward direction.
  • (3S)-hydroxyhexadecanoyl-CoA + NAD+ = 3-oxohexadecanoyl-CoA + H+ + NADH
    This reaction proceeds in the forward direction.
  • (3S)-hydroxyhexadecanoyl-CoA = (2E)-hexadecenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • (3S)-hydroxyhexanoyl-CoA = (2E)-hexenoyl-CoA + H2O
    This reaction proceeds in the backward direction.
  • (3Z)-hexenoyl-CoA = (2E)-hexenoyl-CoA
    This reaction proceeds in the forward direction.
  • a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA
    This reaction proceeds in the forward direction.
    EC:5.3.3.8 (UniProtKB | ENZYME | Rhea)
  • a (3S)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + H+ + NADH
    This reaction proceeds in the forward direction.
    EC:1.1.1.35 (UniProtKB | ENZYME | Rhea)
  • a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA
    This reaction proceeds in the forward direction.
    EC:5.3.3.8 (UniProtKB | ENZYME | Rhea)
  • a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O
    This reaction proceeds in the forward direction.
    EC:4.2.1.17 (UniProtKB | ENZYME | Rhea)

Pathway

Lipid metabolism; fatty acid beta-oxidation.

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functionenoyl-CoA hydratase activity
Molecular FunctionNAD+ binding
Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Processfatty acid beta-oxidation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxisomal bifunctional enzyme
  • EC number
  • Alternative names
    • Multifunctional enzyme 1

Gene names

    • ORF names
      EPR50_G00119020

Organism names

  • Taxonomic identifier
  • Strain
    • YP-PL-M2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Percinae > Perca

Accessions

  • Primary accession
    A0A484CVY3

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain304-4773-hydroxyacyl-CoA dehydrogenase NAD binding
Domain480-5843-hydroxyacyl-CoA dehydrogenase C-terminal
Domain621-7063-hydroxyacyl-CoA dehydrogenase C-terminal

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family.
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    725
  • Mass (Da)
    78,815
  • Last updated
    2019-06-05 v1
  • Checksum
    220BA8A234B9068F
MCDKGSMAQYTRVSGFVGLITLQNPPVNALSAAVRQGIVDMVERALSDPIVKSVVICGQNGNFCGGADIKEFGTNMSGPPLVPMIDAIEAANKPVVAAIEGSALGGGLELALGCHYRIAHSKARLGLPEVTLGLLPAAGGTQRLSRLIGVPAALNLITTGIHVTAAQALQLGIVDQVTDHNAVEVAVTFSLSVAGQSMDARRISTYPCPLPSDFDALFEGVMQKVRQSARGAIAPVACVQAVRAAATLPYTKGMEREQELMATLFTSGQARAQQYCFFAQRAVGRWRMPSGARWETSKPMPVHKAAVIGLGTMGRGITVALAQTGLSVVAVETQEKQLMEAKQAVSGMLERGAKRHGVAPMLDRISYSQNIQAVAEVDLVIEAVFEDMALKTEVFQQLSAVCKPGTLLCTNTSALDVDKLASEMPNPELVVGMHFFAPAHVMKLLEVVYGPRSSPQAVATAMQLGKKMGKVSVAVGNCRGFVGNRMLMPYLQQAFFLLEEGATPELVDRALEEFGFPMGVFRMSDLSGLDIGWRVRKRDELVEPDMASGQSARIRQGSRYSPLGDLLCEQGRFGQKTGQGWYRYDKPGSRVARSDPWLHSFLVEYRARHGLVPRSIDHQEVLERCLYALINEGFRILEDGIAAGPEDIDVIYVFGYGWPRHRGGPMFYASMVGLAKILERLEHYQQAHPDVPYLQPSSLLRRLVASDSPPIHRWREVIKKYQSQL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCKG01000011
EMBL· GenBank· DDBJ
TDH06990.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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