A0A484CDB8 · A0A484CDB8_PERFV

Function

function

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.
    EC:5.6.1.1 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

151950100150200250300350400450500
TypeIDPosition(s)Description
Binding site275-282ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmicrotubule
Cellular Componentspindle pole
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionisomerase activity
Molecular Functionmicrotubule binding
Molecular Functionmicrotubule severing ATPase activity
Biological Processanatomical structure morphogenesis
Biological Processmicrotubule severing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Katanin p60 ATPase-containing subunit A-like 2
  • EC number
  • Short names
    Katanin p60 subunit A-like 2
  • Alternative names
    • p60 katanin-like 2

Gene names

    • Name
      KATNAL2
    • ORF names
      EPR50_G00167400

Organism names

  • Taxonomic identifier
  • Strain
    • YP-PL-M2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Percinae > Perca

Accessions

  • Primary accession
    A0A484CDB8

Proteomes

Subcellular Location

Cytoplasm, cytoskeleton
Cytoplasm
Note: Localizes within the cytoplasm, partially overlapping with microtubules in interphase and to the mitotic spindle and spindle poles during mitosis.

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region95-155Disordered
Compositional bias120-150Polar residues
Domain267-405AAA+ ATPase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    519
  • Mass (Da)
    57,694
  • Last updated
    2019-06-05 v1
  • MD5 Checksum
    7A7F153FFBD8AC08C8E49B0BACAD6983
MMELSYQSMKVAHQAREADELRTEMRRKSLLILIYHHLLGQGYVSAAVALDQETNGGVRRFEVCDNIDLEMVLMEYESYHYVKFQKYPKLIRRTAEPGENRNARSGSIKRSPCSAAKPLPKINPSQTPKSGNGAKRTTASSHTNENGSAVPPELSEFGLNVSSIRNGSAGEAANNRKGQMTDGKVSIQGAGSDSDYMERLLKPLSGFSGMSGEMRELAAIISRDIYLHSPNVRWEDIIGLEDAKRLVKEAVVYPIKYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASSIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTSMGGEHEGSRRMKTELLVQMDGLAKSEDLVFVLAASNLPWELDHAMLRRLEKRIIVSLPSSPARQAMISHWLPPLSSTGGVELRTELDYETLAKGMEGYSGSDIRLVCKEAAMRPVRKIFDALESHQDGDTDVPAIQLETVTTADFLEVITHTKPSARNLMDKYTAWEREYESV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias120-150Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCKG01000016
EMBL· GenBank· DDBJ
TDH01889.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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