A0A484CAP7 · A0A484CAP7_PERFV

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site255Nucleophile
Active site339
Active site341

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Uncharacterized protein

Gene names

    • ORF names
      EPR50_G00191190

Organism names

  • Taxonomic identifier
  • Strain
    • YP-PL-M2
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Percinae > Perca

Accessions

  • Primary accession
    A0A484CAP7

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain521-713ATP-grasp
Domain1057-1248ATP-grasp
Domain1313-1469MGS-like
Region1818-1885Disordered
Compositional bias1831-1846Basic and acidic residues

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,235
  • Mass (Da)
    247,619
  • Last updated
    2019-06-05 v1
  • Checksum
    9DFEDC4BD91FCB04
MTKMATLILEDGTTFKGLLFGANVSVSGEVVFQTGMVGYPEALTDPSYRCQLLTLTYPLVGNYGVPQDEEGEFGLSKWFESSKIHAAALIIGELSESPSHWSSARSLDQWLKEQGVPGIQGIDTRRLTKKIREKGTMLGKLVVDGTPQDSIPFDNPDKRNLVQEVSMKEPKVFNPSGSLRITVVDCGIKYNQIRCLAQRGACVTVVPWDHPLDSTDFDGLFISNGPGDPQLCQTTINNMRKVVCVDRPKPVFGICLGHQLLSLLIGSKTYKMKYGNRGHNQPCIHKGTDRCFITSQNHGFAVDPDTLPKDWDVLFTNANDHTNEGIVHNTKPLFSVQFHPEHMAGPTDLVGLFDVFLETVKDHKEGNATKSVKQRLTDHLTYAGSPKPEEEVFRPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITAEYVTQVIKNERPDGVLLTFGGQTALNCGVELTKLGVLEKYKVRVLGTPVASIEMTEDRKIFVEKMEEINEHVAPSEAALSVEQAVAAAERLGYPVLVRSAFALGGLGSGFANNREELTSLVTSAFAHTSQVLVDKSLKGWKEIEYEVVRDAYDNCVTVCNMENIDPLGIHTGESIVVAPSQTLNDHEYNMLRNTAIKVIRHLGIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLGLGIPLPLLKNSVTNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTTIGSSMKSVGEVMAIGRSFEEAFQKALRMVDENCVGFDHTIKPVSDEELQTPTDKRIFVLASAFRGGYTVDQLYELTKIDRWFLHKMKNITDHERLLETYNQDEGVMPPEVMRKAKQLGFSDKQIAQAVQSTELVVRKLRHDWSILPVVKQIDTVAAEWPAHTNYLYLTYHGTEDDLGFDDQHVMVIGSGVYRIGSSVEFDWCAVGCITELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYERENPEGVILSMGGQLPNNIAMSLHRQQCRILGTSPEFIDCAENRFKFSRMLDTIGISQPQWKELSDTESAWKFCETVGYPCLVRPSYVLSGAAMNVAYSDSDLEKYLTNAVAVSKEHPVVISKFIQEAKEIDVDAVACDGVVMAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKIIVHAIGLELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATQAIVGEDVQPVGLMRGKGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNILLSIGSYKNKSELLPTVQALESMGYDLYASLGTADFYTEHGVKVKAVDWPFEEEDSDCPTKEKQRSIMDYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLIIDIKCTKLFVQALHQIGRTPPVKTHIDCMTSQTLVRLPGLIDVHVHLREPGATHKEDFSSGTAAALAGGVTMVCAMPNTSPAITDASTLALVQKLAKAGCRCDYALYLGAASDNAAVLPSIASQAAGLKMYLNDTYSTLKMDNVSLWMEHFEKWPKQMPIVAHAEKQTVAAILMVAQLYQRPVHICHIAKKEEILIIRAAKQKGIQVTCEVAPHHLFLCEENMSEIGVGRAQVRPMLGTKEDMEALWENLDIIDCFATDHAPHSVEEKNGDHPPPGYPGLETMLPLLLTAVSDGRLTMDDIIRRLYDNPRRIFNLPVQDNTYVEVDLEQEWVIPQAMQFTKSKWTPFQGLKVKGKVRRVVLRGEVAYIDGQVLVPPGYGEDVKTWPTASIHPPEPVKESPRTPEHPRPTPPREGPVRTRAPSPRRLTSESRYLLPPRTHRSSDPGLTPEMVMLPAAGAGDGYSHPPPLSRLLSPQSAAGPLPAGQVSHFQTSPLLHPLVGQHILSVRQFSKEQISHLFNVAHTLRLMVQKERSLDILKGKVMASMFYEVSTRTSSSFAAAMQRLGGSVVHFSESTSSVQKGESLADSVQTMSCYADVLVLRHPTPGAVETASRHCRKPVINAGDGVGEHPTQALLDVFTIREELGTVNGMTITMVGDLKHGRTVHSLAKLLTQYRITLRYVAPKNLHMPTEIISYVASKGIRQEEFDSIEEALPETDVLYMTRIQKERFASEEEYKACFGQFVLTPHIMTVAKRKMVVMHPLPRVNEISAEVDTDPRAAYFRQAENGMYIRMALLATVLSR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1831-1846Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SCKG01000018
EMBL· GenBank· DDBJ
TDH00707.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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