A0A482JAX5 · A0A482JAX5_9CAUD

Function

Catalytic activity

Cofactor

adenosylcob(III)alamin (UniProtKB | Rhea| CHEBI:18408 )

Features

Showing features for active site.

167650100150200250300350400450500550600650
TypeIDPosition(s)Description
Active site364
Active site366

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncobalamin binding
Molecular Functionnucleotide binding
Molecular Functionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Molecular Functionribonucleoside-triphosphate reductase (thioredoxin) activity
Biological ProcessDNA replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ribonucleoside-triphosphate reductase (thioredoxin)
  • EC number

Gene names

    • Name
      49
    • ORF names
      SEA_DIRTYDUNNING_49

Organism names

Accessions

  • Primary accession
    A0A482JAX5

Proteomes

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond89↔375Redox-active

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-79Ribonucleotide reductase alpha helical
Domain136-235B12-dependent ribonucleotide reductase insertion
Domain327-480Ribonucleotide reductase large subunit C-terminal

Sequence similarities

Belongs to the class II ribonucleoside-triphosphate reductase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    676
  • Mass (Da)
    75,650
  • Last updated
    2019-06-05 v1
  • Checksum
    D9A702BEE742DBB5
MTTEVKWGPTGEIVYKRTYSRVKPDGSNETWPETVERVVDGNLALVDARYQEPDEREQLIRLITEFKMLPAGRHLWASGVKNAQHLFNCWVSGWTEKPSDHFEFTFMRLMEGGGVGANYSNRFLDYGPVQQELYVHIVCDPEHPDYEAMKEAGVLSTEYDPEWAGAFVIEDSREGWAAALVDLIDTHYRDEVSHFQRVYDVSRVRPFGAKLKTFGGRASGPLPLARMLIDVCEVLSELATEGGSLTGMDAMEIDHAIAQCVVAGGVRRSARMSMMHWADPQIGSFMRCKSETGKHWTTNISVEVDEEFWRVVKETDAKPGWNSNPAAVLKAITEGMVANGEPGFWDSSLSNVGEPNEVVCTNPCGEITLQEWEPCNLGHINLAAFVKENGKVDTIDLVRSHRLMARFLIRATFSPVGDPKSREVLDRNRRIGVGHLGVASFLAMTGKRYSQAPLDKHFRKTLRELAAEVQHAAQKFSHELRIPVPVKTRTVAPTGTIAKMPGVSEGIHPIFAKYFNRRIRFSKGDEQLDELIDQGYDFEPCQYAENTVVVTIPTKDTLVQEVVDRYGRDAEEIVESVEDLTLNQMLAFQAMYQMLWADNAVSFTANVDPDRYKPHVVGEQLRTFGGLLKGATIFPESSMPQAPYERITKKQYKAATAVAVADSVDEECASGACPIR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK494094
EMBL· GenBank· DDBJ
QBP29339.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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