A0A454AA61 · A0A454AA61_ECOL5

Function

function

Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site10ATP (UniProtKB | ChEBI)
Binding site10substrate
Binding site14-19substrate
Binding site17ATP (UniProtKB | ChEBI)
Binding site23-26substrate
Binding site29ATP (UniProtKB | ChEBI)
Binding site29a divalent metal cation (UniProtKB | ChEBI)
Binding site31-35substrate
Binding site48-51substrate
Binding site56substrate
Active site70Proton acceptor
Binding site70substrate
Binding site77ATP (UniProtKB | ChEBI)
Binding site77a divalent metal cation (UniProtKB | ChEBI)
Binding site86-88ATP (UniProtKB | ChEBI)
Binding site95-96ATP (UniProtKB | ChEBI)
Binding site99substrate
Binding site113-118substrate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionmetal ion binding
Biological Processphosphatidic acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diacylglycerol kinase
  • EC number

Gene names

    • Ordered locus names
      ECP_4260

Organism names

Accessions

  • Primary accession
    A0A454AA61

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane57-80Helical
Transmembrane100-121Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the bacterial diacylglycerol kinase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    122
  • Mass (Da)
    13,257
  • Last updated
    2019-05-08 v1
  • MD5 Checksum
    C7E46D2156E8123FA37A0AC3241359FB
MANNTTGFIRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHFG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000247
EMBL· GenBank· DDBJ
ABG72208.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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