A0A452SCP8 · A0A452SCP8_URSAM

Function

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site277
Active site335
Active site358
Binding site398Ca2+ (UniProtKB | ChEBI)
Binding site400Ca2+ (UniProtKB | ChEBI)
Binding site447Ca2+ (UniProtKB | ChEBI)
Binding site452Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentendoplasmic reticulum
Cellular Componentextracellular matrix
Cellular Componentextracellular region
Cellular Componentmitochondrion
Cellular Componentnucleosome
Cellular Componentnucleus
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Molecular FunctionGTP binding
Molecular Functionhistone dopaminyltransferase activity
Molecular Functionhistone serotonyltransferase activity
Molecular Functionpeptidase activity
Molecular Functionpeptide histaminyltransferase activity
Molecular Functionprotein-glutamine gamma-glutamyltransferase activity
Molecular Functionprotein-glutamine glutaminase activity
Biological Processapoptotic cell clearance
Biological Processbranching involved in salivary gland morphogenesis
Biological Processcellular response to cocaine
Biological Processcellular response to dopamine
Biological Processcellular response to serotonin
Biological Processdopamine secretion
Biological Processgene expression
Biological Processnegative regulation of endoplasmic reticulum calcium ion concentration
Biological Processphospholipase C-activating G protein-coupled receptor signaling pathway
Biological Processpositive regulation of apoptotic process
Biological Processpositive regulation of cell adhesion
Biological Processpositive regulation of mitochondrial calcium ion concentration
Biological Processpositive regulation of neurogenesis
Biological Processproteolysis
Biological Processregulation of apoptotic cell clearance
Biological Processsalivary gland cavitation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamine gamma-glutamyltransferase 2
  • EC number
  • Alternative names
    • Isopeptidase TGM2
    • Protein-glutamine deamidase TGM2
    • Protein-glutamine dopaminyltransferase TGM2
    • Protein-glutamine histaminyltransferase TGM2
    • Protein-glutamine noradrenalinyltransferase TGM2

Gene names

    • Name
      TGM2

Organism names

Accessions

  • Primary accession
    A0A452SCP8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain269-361Transglutaminase-like

Sequence similarities

Belongs to the transglutaminase superfamily. Transglutaminase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    687
  • Mass (Da)
    77,054
  • Last updated
    2019-05-08 v1
  • Checksum
    00089BA9AAF4D97F
MAEDLVLEKCDLELEVNGRDHHTADLCRDRLVVRRGQPFWLTLHFEGRSYEASVDSLTFSAVTGPAPREEAGTKARFPLASAVEEGAWTAVAMDQQDGVLSLQLSTPANAPIGLYRLSLEASTGYQGSSFVLGHFTLLFNTWCPADAVYLDSEEERQEYVLTQQGFIYQGSVKWIKSIPWNFGQFEDGILDICLTLLDMNPKFLKDACRDCSRRSSPVYMARVVSAMVNCNDDQGVLLGRWDNNYKDGISPMFWIGSVDILRRWKTSGCQRVKYGQCWVFAAVACTVLRCLGVPTRVVTNFNSAHDQNSNLLIEYVYDKSGEIQRDKSEMIWNYHCWAESWMSRPDLQPGYDGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVNWIVQEDGSMCKSTNNSQTVGMKISTKSVGRDEREDITHTYKYPEGSPEEREAFKRANHLNKLTDKVETGVAMRVRVAQSVSVGSDFDVFAHITNNTAESLTCRLLLLARTVSYNGVLGPECGTKDLLNLSLEPFSEKSIPLRILYEKYCECLTESNLIKVRGLLMEPAANNYLLAERDIYLENPEIKIRILGEPKQNRKLVAEASLWNPLTMPLLGCTFTMEGAGLTEEQKIMDVPDPVEAGEEVKVRVDLLPCHVGRHKLVVNFDSDKLKAVKGFRNIIIGPA

Keywords

Genome annotation databases

Similar Proteins

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