A0A452QWU7 · A0A452QWU7_URSAM

Function

function

Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functioncysteine-tRNA ligase activity
Molecular Functionmetal ion binding
Biological Processcysteinyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cysteine--tRNA ligase, cytoplasmic
  • EC number
  • Alternative names
    • Cysteinyl-tRNA synthetase

Gene names

    • Name
      CARS1

Organism names

Accessions

  • Primary accession
    A0A452QWU7

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain122-495tRNA synthetases class I catalytic
Region730-749Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    777
  • Mass (Da)
    88,148
  • Last updated
    2019-05-08 v1
  • Checksum
    C6F5B57BF9CC8C21
MLCASVFAAPAYSSILSISDEAARVQALNEHLSTRSYVRGYSLSQADVDVFRQLSAPPADTRLFHVARWFRHIEAILGGPCGRGEPCKGRREQPQWSPPAGSPPCKLRLYNSLTRSKDVFIPQHGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFGYDVFYCMNITDVDDKVRLPHVVNAVRDPHTTDPDKKQMLERIQHAVKLAAEPLERAMQSDLPAAVADEAKDLLSDWLDCALGSEVTDNSIFSQLPKFWEEEFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTAKFASSERHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFLNVKDILRAPVDITGRFEKWEDEESELNESFYDKKAAVHEALCDNVDTRTVLEEMRALVSRCNLYMAARKAARRRPNRALLESIALYLTHMLTIFGAIEEESSLGFPVRGPGTSLDLESTVMPYLQVLSEFREGVRKIAREQKVPEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLGDREALLREREEKRQVRPVFQAAKLAKMKIPPSEMFLSESDKYSKFDENGLPTHDTEGKELSKGRAKKLRKLFEAQEKLYKEYLQAVQTGSFQ

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A452QWK7A0A452QWK7_URSAMCARS1817
A0A452QWV1A0A452QWV1_URSAMCARS1789
A0A452QWP2A0A452QWP2_URSAMCARS1814
A0A452QWQ1A0A452QWQ1_URSAMCARS1811
A0A452QWN3A0A452QWN3_URSAMCARS1814
A0A452QWH6A0A452QWH6_URSAMCARS1749
A0A452QWH7A0A452QWH7_URSAMCARS1816
A0A452QWK4A0A452QWK4_URSAMCARS1798
A0A452QWG4A0A452QWG4_URSAMCARS1665

Keywords

Genome annotation databases

Similar Proteins

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