A0A452QTY7 · A0A452QTY7_URSAM

Function

Catalytic activity

Features

Showing features for binding site, active site.

1793100200300400500600700
Type
IDPosition(s)Description
Binding site401substrate
Active site433Phosphocysteine intermediate
Binding site433-439substrate
Binding site477substrate
Active site723Phosphocysteine intermediate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionprotein tyrosine phosphatase activity
Biological Processprotein dephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Receptor-type tyrosine-protein phosphatase alpha
  • EC number

Gene names

    • Name
      PTPRA

Organism names

Accessions

  • Primary accession
    A0A452QTY7

Proteomes

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane143-166Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, modified residue.

Type
IDPosition(s)Description
Signal1-19
ChainPRO_501882456420-793Receptor-type tyrosine-protein phosphatase alpha
Modified residue789Phosphotyrosine

Keywords

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region108-136Disordered
Domain232-492Tyrosine-protein phosphatase
Domain412-483Tyrosine specific protein phosphatases
Domain524-782Tyrosine-protein phosphatase
Domain698-773Tyrosine specific protein phosphatases

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    793
  • Mass (Da)
    89,668
  • Last updated
    2019-05-08 v1
  • Checksum
    0EBBDCA090EBDDC8
MDSWFILVLLGSSLTRVGANNATTVSPSVGVTRSMKTSTAESVKEETKASNHTSSVTSLSVAPTFSPNLTLGPTYVTTVNSSDSDNGTTRTASTDSVVTTLAPNGTWLPENQFTDASTEPWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGVVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A452QTW6A0A452QTW6_URSAMPTPRA802

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help