A0A452QQU9 · A0A452QQU9_URSAM

Function

function

Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site80Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase kinase kinase activity
Molecular Functionprotein serine kinase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitogen-activated protein kinase kinase kinase kinase
  • EC number

Gene names

    • Name
      MAP4K3

Organism names

Accessions

  • Primary accession
    A0A452QQU9

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain1-207Protein kinase
Compositional bias324-347Polar residues
Region324-375Disordered
Compositional bias348-366Pro residues
Region390-416Disordered
Domain435-752CNH

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    768
  • Mass (Da)
    87,761
  • Last updated
    2019-05-08 v1
  • Checksum
    3076692E0E0EBEE7
PGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVSLIFVFCFLKLQGLCYLHSKGKMHRDIKVYIISDFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEINFGQVKFDPPLRKETEPHHELPFLHFLKFLLKPFGKVRLVTVELSFVLRGHVPKSIFIPQETHSTEDDNQGTIKRCPTSESPAKPSQVPPRPPPPRLPPQKPIALGNGVSSFQLNGERDGSLYQQQNEHRGTNPSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVSIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRVFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDSPQTSVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFRIESIVCLQDSVLAFWKHGMQGRSFRSNEVIFKNNFCLFITFRVVVLESRPTDNPTANSNLYILAGHENSY

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A452QR03A0A452QR03_URSAMMAP4K3810
A0A452QQY1A0A452QQY1_URSAMMAP4K3749
A0A452QQY6A0A452QQY6_URSAMMAP4K3763
A0A452QQV5A0A452QQV5_URSAMMAP4K3666
A0A452QR19A0A452QR19_URSAMMAP4K3761
A0A452QQN4A0A452QQN4_URSAMMAP4K3795
A0A452QR02A0A452QR02_URSAMMAP4K3763

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias324-347Polar residues
Compositional bias348-366Pro residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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