A0A452QJ28 · A0A452QJ28_URSAM
- Proteinnon-specific serine/threonine protein kinase
- GeneMAP4K1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids631 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 23-31 | ATP (UniProtKB | ChEBI) | |||
Binding site | 46 | ATP (UniProtKB | ChEBI) | |||
Active site | 137 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | histone H2AS1 kinase activity | |
Molecular Function | MAP kinase kinase kinase kinase activity | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namenon-specific serine/threonine protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Ursidae > Ursus
Accessions
- Primary accessionA0A452QJ28
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 17-274 | Protein kinase | |||
Region | 297-328 | Disordered | |||
Compositional bias | 299-313 | Basic and acidic residues | |||
Region | 348-438 | Disordered | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length631
- Mass (Da)69,870
- Last updated2019-05-08 v1
- MD5 ChecksumA13714CA1D4B4E375761E6D8A69BC288
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A452QJ31 | A0A452QJ31_URSAM | MAP4K1 | 851 | ||
A0A452QJ40 | A0A452QJ40_URSAM | MAP4K1 | 774 | ||
A0A452QJ14 | A0A452QJ14_URSAM | MAP4K1 | 413 | ||
A0A452QJ26 | A0A452QJ26_URSAM | MAP4K1 | 701 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 299-313 | Basic and acidic residues | |||
Keywords
- Technical term