A0A452QGB7 · A0A452QGB7_URSAM
- ProteinGlycogen [starch] synthase
- GeneGYS2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids618 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Catalytic activity
- [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + UDP + H+This reaction proceeds in the forward direction.
[(1→4)-α-D-glucosyl](n) RHEA-COMP:9584 + CHEBI:58885 = [(1→4)-α-D-glucosyl](n+1) RHEA-COMP:9587 + CHEBI:58223 + CHEBI:15378
Pathway
Glycan biosynthesis; glycogen biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity | |
Biological Process | glycogen biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycogen [starch] synthase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Ursidae > Ursus
Accessions
- Primary accessionA0A452QGB7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 553-618 | Disordered | |||
Compositional bias | 604-618 | Basic residues | |||
Sequence similarities
Belongs to the glycosyltransferase 3 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length618
- Mass (Da)71,182
- Last updated2019-05-08 v1
- ChecksumFD248FE186C5DF55
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A452QG98 | A0A452QG98_URSAM | GYS2 | 708 | ||
A0A452QGD5 | A0A452QGD5_URSAM | GYS2 | 686 | ||
A0A452QGE7 | A0A452QGE7_URSAM | GYS2 | 677 | ||
A0A452QGE9 | A0A452QGE9_URSAM | GYS2 | 630 | ||
A0A452QG73 | A0A452QG73_URSAM | GYS2 | 702 | ||
A0A452QG96 | A0A452QG96_URSAM | GYS2 | 703 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 604-618 | Basic residues | |||
Keywords
- Technical term