A0A452QDP5 · A0A452QDP5_URSAM

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentvoltage-gated potassium channel complex
Molecular Functionpotassium channel regulator activity
Molecular Functionserine-type peptidase activity
Biological Processproteolysis
Biological Processregulation of potassium ion transmembrane transport

Names & Taxonomy

Protein names

  • Recommended name
    A-type potassium channel modulatory protein DPP6
  • Alternative names
    • Dipeptidyl aminopeptidase-like protein 6
    • Dipeptidyl peptidase 6
    • Dipeptidyl peptidase VI

Gene names

    • Name
      DPP6

Organism names

Accessions

  • Primary accession
    A0A452QDP5

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-36Helical

Keywords

  • Cellular component

Interaction

Subunit

Homodimer (in vitro). Interacts with KCND2. Identified in a complex with KCND2 and KCNIP2. Forms an octameric complex composed of four DPP6 subunits bound to the KCND2 tetramer. Interacts with KCND3; this interaction modulates the channel gating kinetics namely channel activation and inactivation kinetics and rate of recovery from inactivation.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain82-416Dipeptidylpeptidase IV N-terminal
Domain498-548Peptidase S9 prolyl oligopeptidase catalytic
Domain585-654Peptidase S9 prolyl oligopeptidase catalytic

Sequence similarities

Belongs to the peptidase S9B family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    671
  • Mass (Da)
    76,097
  • Last updated
    2019-05-08 v1
  • Checksum
    A2437134F9EA02B3
MRTAFSSQPHQYSVLYFFFGGGSISVLISIILHYLVLFNTSEDLLYPLCGLSLEDKQRTFLFPTILIDWLIDYLSIYLFSFRDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYATINDSRVPIMELPTYTGSIYPTVKPYHYPKAGCENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVNWLSRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGQGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILSYDEKRNKIYFLSTEDLPRRRQLYSASTVGTFNRQCLSCDLVENCTYFSASFSHSADFFLLKCEGPGVPTVTVHNTTDKKKIFDLETNEHVQKAVQDRQMPKVEYRKIEVDDYNLPVQILKPATFTDTAHYPLLLVVDGTPGSQSVAEKFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEVGRRLGSLEEKDQMEAGENQGQVFTCGSALSPITDFKLYGNGLDMTKVAPRVSGLEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSASLHQHLYRSIINFFVECFRIQDKLPTATAKEEEEED

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A452QCQ9A0A452QCQ9_URSAMDPP6779
A0A452QEA0A0A452QEA0_URSAMDPP6635
A0A452QE09A0A452QE09_URSAMDPP6693
A0A452QDK5A0A452QDK5_URSAMDPP6741
A0A452QDE7A0A452QDE7_URSAMDPP6747
A0A452QD67A0A452QD67_URSAMDPP6764
A0A452QCR0A0A452QCR0_URSAMDPP6721
A0A452QCE1A0A452QCE1_URSAMDPP6749
A0A452QCE9A0A452QCE9_URSAMDPP6751

Keywords

Genome annotation databases

Similar Proteins

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