A0A449B5Z3 · A0A449B5Z3_9BACT

Function

function

Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; NAD+ from deamido-NAD+ (ammonia route): step 1/1.

Features

Showing features for binding site.

126320406080100120140160180200220240260
TypeIDPosition(s)Description
Binding site51Mg2+ (UniProtKB | ChEBI)
Binding site126deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site146ATP (UniProtKB | ChEBI)
Binding site151Mg2+ (UniProtKB | ChEBI)
Binding site159deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain
Binding site166deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits
Binding site175ATP (UniProtKB | ChEBI)
Binding site197ATP (UniProtKB | ChEBI)
Binding site251-252deamido-NAD+ (UniProtKB | ChEBI); ligand shared between two neighboring subunits; in other chain

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionglutaminase activity
Molecular Functionmetal ion binding
Molecular FunctionNAD+ synthase (glutamine-hydrolyzing) activity
Molecular FunctionNAD+ synthase activity
Biological ProcessNAD biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NH(3)-dependent NAD(+) synthetase
  • EC number

Gene names

    • Name
      nadE
    • ORF names
      NCTC10179_00183

Organism names

  • Taxonomic identifier
  • Strain
    • NCTC10179
  • Taxonomic lineage
    Bacteria > Mycoplasmatota > Mycoplasmoidales > Metamycoplasmataceae > Mycoplasmopsis

Accessions

  • Primary accession
    A0A449B5Z3

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-254NAD/GMP synthase

Sequence similarities

Belongs to the NAD synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    29,134
  • Last updated
    2019-05-08 v1
  • Checksum
    274264B1D4BCFD59
MSKITSYQNNKAIYNKETALKYLATIERFLKNKVAKAHAQGVVVGISSGIDSSLVFAIAKRVFGAKAIGVVMPVIKMTQSDLNHIKELEIATNSKFMVKDLTKTFESITQELQVSNPLAVANIKPRLRMTTLYAIAQENNSLVLGTDNADEVFVGYFTKFGDGGADLLPISKLTKGEVAYLASLVGVPESIIKKDPSAGLWEGQTDEQELGFSYAQLDFYLNHLNEPKKLKEVLSDKVIAKIEQLHKNSQHKRDRIYTPVNVK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR215039
EMBL· GenBank· DDBJ
VEU76021.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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