A0A448YF77 · A0A448YF77_BRENA

Function

function

ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2.
RNA helicase.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentnucleolus
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological ProcessrRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase
  • EC number

Gene names

    • ORF names
      BRENAR_LOCUS298

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Pichiaceae > Brettanomyces

Accessions

  • Primary accession
    A0A448YF77

Proteomes

Subcellular Location

Interaction

Subunit

Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif, compositional bias, region.

Type
IDPosition(s)Description
Domain43-71DEAD-box RNA helicase Q
Motif43-71Q motif
Domain74-248Helicase ATP-binding
Domain274-433Helicase C-terminal
Compositional bias635-698Basic and acidic residues
Region635-787Disordered
Compositional bias714-734Acidic residues
Compositional bias735-754Basic and acidic residues

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    787
  • Mass (Da)
    89,479
  • Last updated
    2019-05-08 v1
  • Checksum
    F41411EC3BCA00C8
MPRNTKAISREDKRRLRHKRKENLEDLKKRVEEFDPVENSKITKFDELPLTQETLRGLGESGYVNLTDIQREAIPICLQGHDVLGAAKTGSGKTLSYLIPVLERLNYEKWSDMDGVGALIILPTRELAVQIYEVLLRIGKFSSLSAGLVIGGKDYKFEKERIGKVNILIGTPGRILQHLDESSTLNLDNLQTLVLDEADRILDMGFRQTIDSILNDIPPQRQTLLFSATQTKSVKDLARLSLVNPKYISTSTDQEATTPESLDQFCVTTQLSEKLDLLWSFIKAHINTKILVFVSSSKQVHFIYESFRKLRPGIQLLKLHGRQKQKARMETTQQFTHASHCCLFATDVVARGLDFPAIDWVIQLDCPEDVTTYIHRVGRSARFGRSGKSLLMLTPNEETPFLKKLGSRKIAVKKLNVKGSKKKSIHSQLQSLCFESPELKYLGQKAFISYCKSVFVQADKEVFDLSKLPLEEYAKSLGLPGTPKVKFMDRAREGKGMSEGEITKVKAKKNASRKVMNLAKTDENGEAMEEKRVRTKYDKMFERTNQNILSEHYMQMTHGKAGEYDDDDDDGDFLTVRRTVDDVDEKDLPPLELINTSKRAMKRATSRKLTAKMQDKGSKMVFDDAGKAHAVYELENEEDFQKQGPADELKEQFLSGEKANMHKEDAVDKSVAKEKRVEKKRRRKELERLAKEDEVSDEEAAYTVVLGHGSEDDEEPDLERDLALGEEEEREKDDENKEEERPSKRTKMVAEPQEEDGDGGEEGNVIEIEQPESIQDLEALTEKLINE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias635-698Basic and acidic residues
Compositional bias714-734Acidic residues
Compositional bias735-754Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAACVR010000001
EMBL· GenBank· DDBJ
VEU19561.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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